When legendary hunter Bob Rainsford is shipwrecked on the perilous reefs surrounding a mysterious island, he finds himself the guest of the reclusive and eccentric Count Zaroff. While he is very gracious at first, Zaroff eventually forces Rainsford and two other shipwreck survivors, brother and sister Eve and Martin Towbridge, to participate in a sadistic game of cat and mouse in which they are the prey and he is the hunter.
Ruth Earlton has come home to her ancestral mansion to claim her inheritance. Accompanied by her boyfriend, she discovers that her father died suddenly under suspicious circumstances. Now it's her turn, as her deranged and relentless uncle targets her for death with the help of his wife and son, plus a very unhappy ape.
Francis, a young man, recalls in his memory the horrible experiences he and his fiancée Jane recently went through. Francis and his friend Alan visit The Cabinet of Dr. Caligari, an exhibit where the mysterious doctor shows the somnambulist Cesare, and awakens him for some moments from his death-like sleep.