Knowing the railroad is coming, Carter is after the rancher's land. Bob and Chito return just in time to save Banker Stockton and his money from Carter's men. When Stockton then lends the ranchers money, Carter has them burned out. Bob knows Carter is responsible and when Carter's henchman Saunders is recognized, Bob goes into action.
Notorious shootist and womanizer Quirt Evans' horse collapses as he passes a Quaker family's home. Quirt has been wounded, and the kindly family takes him in to nurse him back to health against the advice of others. The handsome Evans quickly attracts the affections of their beautiful daughter, Penelope. He develops an affection for the family and their faith, but his troubled past follows him.
To get the Delaney ranch Cole's henchman Anders has started a phony range war between the cattlemen and sheepmen. After killing Delaney, he tries to kill his daughter Jill and then Roy who was sent to investigate the war. But the failed attempts gives Roy the information he needs.
Buster Crabbe and Johnny Weissmuller battle it out in Cajun country! Johnny, a riverboat pilot on the Mississippi, is seduced away from his fiance (Carol Thurston) by a rich outsider (Virginia Grey) who's nursed him back to health after a serious accident. She owns a large piece of the swamp and has outlawed hunting on her property. His rival Mike (Crabbe) is a trapper who harbors deep resentment for Johnny and his new wealthy friends. When he feels Johnny is responsible for the hunting ban, he resorts to destructive acts of vengeance.
Rodeo star Roy Rogers returns home to find that his old friend Tom Craig has been murdered after he was accused of stealing a family crest from Helen Williams. Helen joins up with Roy and Gabby Whittaker to find the killers and the crest.
Gabby doesn't want to breed his horse the Golden Sovereign with Roy's. When Sovereign and Roy's horse escape, the Sovereign gets shot accidentally by Skoville but Roy is blamed and jailed. A year later Roy returns with Trigger, the son of the Sovereign. When Skoville reveals he was present when the horse was shot, Roy sees an opportunity to clear his name.
A young outlaw gets involved with a gang of crooks. When he tells them he is breaking away, they threaten to pin a false murder charge on him. But he is rescued and reformed by his sister, and an undercover agent for the express company.
During World War II, a young boy and girl, living with their respective families in an apartment house that had restrictions against pets, adopt a lost dog and hide it in a vacant apartment, which may have been the only vacant apartment in the United States at the time this movie was being filmed. A burglar breaks in and the apartment is damaged when the dog and crook have a tussle. This blows the dog's cover, but the kids enlist him in the K-9 Corps, and the dog distinguishes himself in the WWII Italian campaign
After some gun play with a posse, the James Gang head for Quinto in a section of land which is not a part of America. Anyone there is beyond the law so the town is populated with outlaws. Next to arrive is Sheriff Rowley, following his brother whom the Gang have brought in injured. Rowley has no authority and gets on well enough with the James boys but is soon involved in other local goings-on, including a move to vote for annexation with Oklahoma which would allow the law well and truly in.
Roy Rogers rides to the rescue when a bank robber's orphaned son (Tommy Cook), who is living at a ranch for homeless boys run by Gabby Whittaker (George "Gabby" Hayes), attracts the attention his father's rowdy gang, who want to claim the boy's inheritance for themselves
Cutthroat pirate William Kidd captures Admiral Blayne's treasure ship and hides the bounty in a cave. Three years later, Kidd, posing as a respectable merchant captain, offers his services to the King of England. Seeking a social position, Kidd also negotiates for Blayne's title and lands, provided he can prove Blayne was associated with piracy. Launched upon his royal mission, Kidd is unaware that Blayne's son Adam is among the crew, determined to clear his father's name.
Wildcat Kelly has been dead and buried for years. Or has he? Dale is a reporter for an Eastern magazine who comes West to find out the true story of Kelly, of whom Gabby seems to have mysterious knowledge.
The story involves a rather odd flashback by Dale who is visiting El Dorado, home of her grandmother. She dreams about her grandmother's adventures including a romance with a cowboy who looks very much like Roy. Roy, of course, also exists in the present for Dale.
Heading west for his health, Colonel Lambeth takes his daughter Rill along. Lost on the desert they are saved by Pecos and Chito. The Colonel hires the two and the Lambeths soon find themselves mixed up in Pecos' trouble. Pecos has killed Sawtelle's brother and Sawtelle as head of the vigilantes is after him.
During World War II, an American mission hospital is headed up by Dr. Gray Thompson and Dr. Sara Durand. Sara is secretly in love with Gray but hides her feelings as his new wife, Louise, arrives at the hospital. Sparks fly, however, when Louise becomes jealous of Sara, and then tries to convince her husband to leave war-torn China behind for a calmer life in the United States. But Thompson is attached to both Sara and the people who need his help.