A medical examiner discovers that an innocent shooting victim in a robbery died of bubonic plague. With only 48 hours to find the killer, who is now a ticking time bomb threatening the entire city, a grisly manhunt through the seamy underworld of the New Orleans Waterfront is underway.
A telephone repairman in Los Angeles uses his knowledge of electronics to help a bookie set up a betting operation. After the bookie is murdered, the greedy technician takes over his business. He ruthlessly climbs his way to the top of the local crime syndicate, but then gangsters from a big East Coast mob show up wanting a piece of his action.
Singer Steve, friend Seymour and fiance Jane, along with her dizzy blonde room mate Irma, have a series of misadventures on a California-bound train and end up involved with a gang of murderous gangsters in Las Vegas.
While executing an armored car heist in Los Angeles, icy crook Dave Purvis shoots policeman Lt. Phillips before he and his cronies make off with the loot. Thinking he got away scot-free, Purvis collects his money-crazy mistress, Yvonne, then disposes of his partners and heads out of town. What Purvis doesn't know is that Phillips' partner, tough-as-nails Lt. Cordell, is wise to the criminal's plans and is closing in on his prey.
Recently paroled from prison, legendary burglar "Doc" Riedenschneider, with funding from Alonzo Emmerich, a crooked lawyer, gathers a small group of veteran criminals together in the Midwest for a big jewel heist.
Al Goddard, a detective who works for the United States Postal Inspection Service, is assigned to arrest two criminals who've allegedly murdered a U.S. postal detective.
Young auto mechanic Dan Brady takes $20 from a cash register at work to go on a date with blonde femme fatale Vera Novak. Brady intends to put the money back before it is missed, but the garage's bookkeeper shows up earlier than scheduled. As Brady scrambles to cover evidence of his petty theft, he fast finds himself drawn into an ever worsening "quicksand" of crime.
The Los Angeles police know that Pete Ritchie has been bringing drugs into the city, but they can't pin a single piece of evidence on him. After many botched attempts to get at the crook, they resort to having cop Madeleine go undercover and seduce her way into Ritchie's circle. Before she can get anywhere, she's abducted by Johnny, a government agent posing as a thug. But Johnny and Madeleine have no idea they're on the same side of the law.
The middle-class family of a young woman cannot understand why she delays in marrying a respectable young man. They know nothing about her long-standing affair with a Frenchman.
When he's discharged from a military hospital, ex-GI Bob Corey goes on a search for his army buddy Steve Connolly. A reformed crook, Connolly is on the lam from a trumped-up murder rap, and Corey hopes to clear his pal. Tagging along is Army nurse Julie Benson, who has fallen for Corey.
Bart Tare is an ex-Army man who has a lifelong fixation with guns, he meets a kindred spirit in sharpshooter Annie Starr and goes to work at a carnival. After upsetting the carnival owner who lusts after Starr, they both get fired. Soon, on Starr's behest, they embark on a crime spree for cash.