Frank Johnson, a sole witness to a gangland murder, goes into hiding and is trailed by Police Inspector Ferris, on the theory that Frank is trying to escape from possible retaliation. Frank's wife, Eleanor, suspects he is actually running away from their unsuccessful marriage. Aided by a newspaperman, Danny Leggett, Eleanor sets out to locate her husband. The killer is also looking for him, and keeps close tabs on Eleanor.
Police catch a break when suspected kidnappers are spotted on a train heading towards Union Station. Police, train station security and a witness try to piece together the crime and get back the blind daughter of a rich business man.
The Skipper is a charming old man loved by all his neighbors. What they don't know is that he is also Mr. 880, an amateurish counterfeiter who has amazingly managed to elude the Secret Service for 20 years.
A medical examiner discovers that an innocent shooting victim in a robbery died of bubonic plague. With only 48 hours to find the killer, who is now a ticking time bomb threatening the entire city, a grisly manhunt through the seamy underworld of the New Orleans Waterfront is underway.
A telephone repairman in Los Angeles uses his knowledge of electronics to help a bookie set up a betting operation. After the bookie is murdered, the greedy technician takes over his business. He ruthlessly climbs his way to the top of the local crime syndicate, but then gangsters from a big East Coast mob show up wanting a piece of his action.
Singer Steve, friend Seymour and fiance Jane, along with her dizzy blonde room mate Irma, have a series of misadventures on a California-bound train and end up involved with a gang of murderous gangsters in Las Vegas.
While executing an armored car heist in Los Angeles, icy crook Dave Purvis shoots policeman Lt. Phillips before he and his cronies make off with the loot. Thinking he got away scot-free, Purvis collects his money-crazy mistress, Yvonne, then disposes of his partners and heads out of town. What Purvis doesn't know is that Phillips' partner, tough-as-nails Lt. Cordell, is wise to the criminal's plans and is closing in on his prey.