In one of his rare performances without Bud Abbott, Lou Costello plays a rubbish collector and inventor. When radiation in a nearby cave turns his girlfriend into a giantess, antics ensue as he tries to shrink her using one of his inventions.
A pathologist experiments with a deaf-mute woman who is unable to scream to prove that humans die of fright due to an organism he names The Tingler that lives within each person on the spinal cord and is suppressed only when people scream when scared.
In California, an old man grieves the loss of his wife, and dies the day after she is buried. However, the space soldier Eros and his mate Tanna use an electric device to resurrect them both, alongside the strong Inspector Clay, who was murdered by the alien-controlled dead couple. When the populations of Hollywood and Washington DC see flying saucers on the sky, a colonel, a police lieutenant, a commercial pilot, his wife and a policeman try to stop the aliens.
A backwoods game warden and a local doctor discover that giant leeches are responsible for disappearances and deaths in a local swamp, but the local police don't believe them.
Fifteen years after his father's experiments with matter transmission fail, Philippe Delambre and his uncle François attempt to create a matter transmission device on their own. However, their experiments have disastrous results, turning Philippe into a horrible half-man, half-fly creature.
Trapped on a remote island by a hurricane, a group discover a doctor has been experimenting on creating half sized humans. Unfortunately, his experiments have also created giant shrews, who when they have run out of small animals to eat, turn on the humans.
A small town in Texas finds itself under attack from a hungry, fifty-foot-long gila monster. No longer content to forage in the desert, the giant lizard begins chomping on motorists and train passengers before descending upon the town itself. Only Chase Winstead, a quick-thinking mechanic, can save the town from being wiped out.
Dr. Bonner plans to live forever through periodic gland transplants from younger, healthier human victims. Bonner looks about 40; he's really 104 years old. But people are starting to get suspicious, and he may not make 200.
A young alien falls for a pretty teenage Earth girl and they team up to try to stop the plans of his invading cohorts, who intend to use Earth as a food-breeding ground for giant lobsters from their planet.
Aliens, contacting scientist Adam Penner, inform him that they have been on the moon for twenty thousand years, undetected due to their invisibility, and have now decided to annihilate humanity unless all the nations of earth surrender immediately. Sequestered in an impregnable laboratory trying to find the aliens' weakness, Penner, his daughter, a no-nonsense army major and a squeamish scientist are attacked from outside by the aliens, who have occupied the bodies of the recently deceased.
Ralph Burton is a miner who is trapped for several days as a result of a cave-in. When he finally manages to dig himself out, he realizes that all of mankind seems to have been destroyed in a nuclear holocaust. He travels to New York City only to find it deserted. Making a life for himself there, he is flabbergasted to eventually find Sarah Crandall, who also managed to survive. Together, they form a close friendship until the arrival of Benson Thacker who has managed to pilot his small boat into the city's harbor. At this point, tensions rise between the three, particularly between Thacker, who is white, and Burton, who is black.
An old lighthouse keeper who lives with his daughter secretly keeps a prehistoric fish-man by feeding it scraps and fish. One day he misses the feeding and all hell breaks loose.
Marine atomic tests cause changes in the ocean's ecosystem resulting in dangerous blobs of radiation and the resurrection of a dormant dinosaur which threatens London.
A college paleontology professor acquires a newly discovered specimen of a coelacanth, but while examining it, he is accidentally exposed to its blood, and finds himself periodically turning into a murderous Neanderthal man.
A missile from parts unknown enters an orbit only 5 miles above Earth's surface and, due to friction from its intense speed through our atmosphere, proceeds to incinerate everything in its immediate wake.
Two escaped convicts are found hiding in a rocketship built by a renegade inventor, who forces them to become the crew for a trip to the Moon. Also on board, as inadvertent stowaways, are his assistant and his secretary; and none of them are aware that the inventor is actually a Lunarian explorer sent to Earth by the dying Lunar civilization and the only remaining male member of that civilization.