Young scout Breck Coleman leads a wagon train along the dangerous trail to Oregon as he tries to get the affection of the beautiful pioneer Ruth Cameron and plans his revenge on the harsh scoundrels who murdered a friend of his in the past.
Billy, after shooting down land baron William Donovan's henchmen for killing Billy's boss, is hunted down and captured by his friend, Sheriff Pat Garrett. He escapes and is on his way to Mexico when Garrett, recapturing him, must decide whether to bring him in or to let him go.
Steve O'Neil robs the stage and kidnaps Nita to keep Lopez from doing the same. Then he and Buckshot head for Lopez's hideout for a showdown. The townspeople head after them not knowing what they will find.
Western sheriff Bob Wells is preparing to marry Sally Morgan; she loves part-Indian Wanenis, whose race is an obstacle. Sally flees the wedding with hypochondriac Henry Williams, who thinks he's just giving her a ride; but she left a note saying they've eloped! Chasing them are jilted Bob, Henry's nurse Mary (who's been trying to seduce him) and others.
Clay gets a musical troop out af jail and helps raise money so they can put on their show. During the performance Blake and his men rob the box office. The townsmen give chase and Clay goes after Blake.
Cattleman Benson finds Mildred and her brother George living in one of his cabins and their sheep are on his land. Attracted to Mildred, he not only lets her stay, he deeds part of his land to her. This leads to trouble with the other cattlemen.
Mysterious bandit has been holding up express shipments from the ranches. The girl's father has a partner who is really the villain, saving the hero who of course is suspected of being the bandit.
Ed King travels east to sell Pop Blake's cattle. While there Buck, another of Blake's hands, plans to rob Ed by using a local girl Ming Toy as a decoy. Ming Toy gets the money and returning empty handed, and before the other hands arrive, Ed is surprised to find Ming Toy return with the men.
Tod Walker takes Rex Carson's map to a gold mine and leaves him in the desert. Carson recuperates at Jean Walker's ranch and she takes a liking to him. But when her uncle Tod arrives, he claims Carson tried to jump his claim. She sides with her uncle and Carson, banished from the Walker ranch, sets out to get his claim back.
Wing Foot is a Navajo educated in an otherwise all-white school. He experiences prejudice from both the whites (because of his race) and the Navajos (who disown him because of his upbringing). Thus, Wing Foot is looked upon as neither Indian nor white, but simply a "redskin".
Capt. James Stewart pursues the bandit "The Kinkajou" over the Mexican border and falls in love with Rita, though he suspects that her brother is the bandit.
Army Sergeant Mickey Dunn sets out in pursuit of the Cisco Kid, a notorious if kind-hearted and charismatic bandit of the Old West. The Kid spends much of his loot on Tonia, the woman he loves, not realizing that she is being unfaithful to him in his absence. Soon, with her oblivious paramour off plying his trade, Tonia falls in with Dunn, drawn by the allure of a substantial reward for the Kid's capture -- dead or alive. Together, they concoct a plan to ambush and do away with the Cisco Kid once and for all.
Bob and Jim Whitely are twin brothers. Bob, an army veteran who suffered shell shock in the war, escapes from a sanitarium and holds up the Express train, for which Jim is mistakenly arrested. Jim soon escapes from jail in order to find his brother. However, his task is complicated by a crooked sheriff who pins a holdup and murder on him that the sheriff himself actually committed. To make matters worse, the murder victim was Tommy Wilkins, the brother of Jim's fiancee, who now thinks that Jim killed her brother.
A deputy comes upon a young girl who has been fired and cheated out of her wages by her former employer. The deputy helps her get what's due her, and accompanies her to her hometown, where they discover that her stepfather has plans to marry her off to a big-time smuggler.
While building an irrigation system for a Southwestern desert community, an engineer vies with a local cowboy for the affections of a rancher's daughter.