Frederick Loren has invited five strangers to a party of a lifetime. He is offering each of them $10,000 if they can stay the night in a house. But the house is no ordinary house. This house has a reputation for murder. Frederick offers them each a gun for protection. They all arrived in a hearse and will either leave in it $10,000 richer or leave in it dead!
Teenagers from a small town and their high school science teacher join forces to battle a giant mutant spider, living in a cave nearby and getting hungry.
A man and wife are terrorized by Mad Scientist Dr. Callistratus who was executed but has returned to life with a heart transplant. Along with his crippled assistant Carl, the 'anemic' Mad Scientist, believed to be a vampire, conducts blood deficiency research on the inmates of a prison hospital for the criminally insane to sustain his return to life.
A United Nations investigator crosses paths with a pair of psychic sisters on his way to Trollenberg observatory in the Swiss Alps, which has been plagued by a series of mountaineer disappearances that may be related to a radioactive cloud at the mountain's south face.
An American airbase in Canada provokes resentment from the nearby residents after fallout from nuclear experiments at the base are blamed for a recent spate of disappearances. A captain from the airbase is assigned to investigate, and begins to suspect that an elderly British scientist who lives near the base and conducts research in the field of mind over matter knows more than he is letting on..
Glenn Manning, "The Amazing Colossal Man," believed dead after falling from the Hoover Dam, reemerges in rural Mexico, brain damaged, disfigured, and very angry.
Two psychics place a prostitute under hypnosis in order to learn about her past-life experiences. When they unwittingly send her back in time, she finds herself in the Middle Ages, suspected of being a witch and on the verge of being executed.
The mysterious Count Orlok summons Thomas Hutter to his remote Transylvanian castle in the mountains. The eerie Orlok seeks to buy a house near Hutter and his wife, Ellen. After Orlok reveals his vampire nature, Hutter struggles to escape the castle, knowing that Ellen is in grave danger. Meanwhile Orlok's servant, Knock, prepares for his master to arrive at his new home.
Francis, a young man, recalls in his memory the horrible experiences he and his fiancée Jane recently went through. Francis and his friend Alan visit The Cabinet of Dr. Caligari, an exhibit where the mysterious doctor shows the somnambulist Cesare, and awakens him for some moments from his death-like sleep.