A mystery writer is intrigued by the tale of notorious criminal Dimitrios Makropolous, whose dead body was found washed up on the shore in Istanbul. He decides to follow the career of Dimitrios around Europe, in order to learn more about the man. Along the way he is joined by the mysterious Mr. Peters, who has his own motivation.
When a woman is found dead with her throat torn out, the local villagers blame a supernatural monster. But Sherlock Holmes, who gets drawn into the case from nearby Quebec, suspects a human murderer.
Sherlock Holmes investigates a series of so-called "pajama suicides". He knows the female villain behind them is as cunning as Moriarty and as venomous as a spider. Based on "The Sign of Four" and the short stories "The Dying Detective", "The Final Problem", "The Speckled Band" and "The Adventure of the Devil's Foot".
Captain Stone's newly recruited officer, Tom Merriam, idolizes his senior who treats him like a friend. But when a couple of his crew members die mysteriously, Tom starts doubting Stone's authority.
During WWII several murders occur at a convalescent home where Dr. Watson has volunteered his services. He summons Holmes for help and the master detective proceeds to solve the crime from a long list of suspects including the owners of the home, the staff and the patients recovering there.
After young Mary Gibson discovers that her older sister Jacqueline has disappeared, she leaves her boarding school and heads to New York City to track down her sibling. But Mary gets drawn deeper into the mystery.
A forger is forced to work for a Nazi spy ring. His conscience gets the better of him, though, and he secretly conspires with the FBI to turn over the gang.
In World War II, a British secret agent carrying a vitally important document is kidnapped en route to Washington. The British government calls on Sherlock Holmes to recover it.
Just when Charlie is feeling especially frustrated by the lack of excitement in her small town in California, she receives wonderful news: Her uncle and namesake, Charlie, is coming to visit. However, as secrets about him come to the fore, her admiration turns into suspicion.
In the midst of World War II, Sherlock Holmes rescues the Swiss inventor of a new bomb-sight from the Gestapo and brings him to England, where he quickly falls into the clutches of the evil Professor Moriarty.
A Serbian émigré in Manhattan believes that, because of an ancient curse, any physical intimacy with the man she loves will turn her into a feline predator.
A high priest of Karnak travels to America with the living mummy Kharis (Lon Chaney Jr.) to kill all those who had desecrated the tomb of the Egyptian princess Ananka thirty years earlier.
England, at the start of World War Two. Mysterious wireless broadcasts, apparently from Nazi Germany are heard over the BBC. They warn of acts of terror in England, just before they take place. Baffled, the Defense Committee call in Sherlock Holmes.