Bumbling professor Ned Brainard accidentally invents flying rubber, or "Flubber", an incredible material that gains energy every time it strikes a hard surface. It allows for the invention of shoes that can allow jumps of amazing heights and enables a modified Model-T to fly. Unfortunately, no one is interested in the material except for Alonzo Hawk, a corrupt businessman who wants to steal the material for himself.
Hans von Arnam travels to a Flemish village to study a strange carousel located in an old windmill that displays famous murderesses and other notorious women from history. Professor Gregorius Wahl, owner of the windmill, warns Hans to stay away from his mysterious daughter Elfi, in order to keep Hans from discovering the horrible secret shared by the Professor and Elfi's Doctor.
Professor Challenger leads an expedition of scientists and adventurers to a remote plateau deep in the Amazonian jungle to verify his claim that dinosaurs still live there.
In a small English village everyone suddenly falls unconscious. When they awake every woman of child bearing age is pregnant. The resulting children have the same strange blond hair, eyes and a strong connection to each other.
The weirdest alien of the galaxy pays a visit to Earth... Jerry Lewis is Kreton, a childish alien who, against his teacher's will leaves his planet to visit the Earth, and lands in the backyard of a famous television journalist who doesn't believe in UFOs and aliens. Wanting to study humans but not able to fully understand them, Kreton makes a mess out of it, generating a lot of comic situations.
The head of a major cosmetics company experiments on herself with a youth formula made from royal jelly extracted from wasps, but the formula's side effects have deadly consequences.
In one of his rare performances without Bud Abbott, Lou Costello plays a rubbish collector and inventor. When radiation in a nearby cave turns his girlfriend into a giantess, antics ensue as he tries to shrink her using one of his inventions.
A pathologist experiments with a deaf-mute woman who is unable to scream to prove that humans die of fright due to an organism he names The Tingler that lives within each person on the spinal cord and is suppressed only when people scream when scared.
Fifteen years after his father's experiments with matter transmission fail, Philippe Delambre and his uncle François attempt to create a matter transmission device on their own. However, their experiments have disastrous results, turning Philippe into a horrible half-man, half-fly creature.
Trapped on a remote island by a hurricane, a group discover a doctor has been experimenting on creating half sized humans. Unfortunately, his experiments have also created giant shrews, who when they have run out of small animals to eat, turn on the humans.
A small town in Texas finds itself under attack from a hungry, fifty-foot-long gila monster. No longer content to forage in the desert, the giant lizard begins chomping on motorists and train passengers before descending upon the town itself. Only Chase Winstead, a quick-thinking mechanic, can save the town from being wiped out.
Dr. Bonner plans to live forever through periodic gland transplants from younger, healthier human victims. Bonner looks about 40; he's really 104 years old. But people are starting to get suspicious, and he may not make 200.
Aliens, contacting scientist Adam Penner, inform him that they have been on the moon for twenty thousand years, undetected due to their invisibility, and have now decided to annihilate humanity unless all the nations of earth surrender immediately. Sequestered in an impregnable laboratory trying to find the aliens' weakness, Penner, his daughter, a no-nonsense army major and a squeamish scientist are attacked from outside by the aliens, who have occupied the bodies of the recently deceased.
Ralph Burton is a miner who is trapped for several days as a result of a cave-in. When he finally manages to dig himself out, he realizes that all of mankind seems to have been destroyed in a nuclear holocaust. He travels to New York City only to find it deserted. Making a life for himself there, he is flabbergasted to eventually find Sarah Crandall, who also managed to survive. Together, they form a close friendship until the arrival of Benson Thacker who has managed to pilot his small boat into the city's harbor. At this point, tensions rise between the three, particularly between Thacker, who is white, and Burton, who is black.
An old lighthouse keeper who lives with his daughter secretly keeps a prehistoric fish-man by feeding it scraps and fish. One day he misses the feeding and all hell breaks loose.