Two friends return home after their discharge from the army after the Civil War. However, one of them has had deep-rooted psychological damage due to his experiences during the war, and as his behavior becomes more erratic--and violent--his friend desperately tries to find a way to help him.
Daniel Bone is aiming for success. A Brooklyn gunsmith by trade, he figures the place to be is where the guns are. So off he goes into the West and becomes the foe of the notorious Pecos Kid, the captive of Paiutes, the target in a saloon showdown, and the lone source of the whereabouts of a fabulous gold strike.
Owen Thursday sees his new posting to the desolate Fort Apache as a chance to claim the military honour which he believes is rightfully his. Arrogant, obsessed with military form and ultimately self-destructive, he attempts to destroy the Apache chief Cochise after luring him across the border from Mexico, against the advice of his subordinates.
Two jobless Americans convince a prospector to travel to the mountains of Mexico with them in search of gold. But the hostile wilderness, local bandits, and greed all get in the way of their journey.
The Bowery Boys head west to clear Louie of an old murder charge that he had killed his gold-mine partner. Sach has the map to the gold mine painted on his back, and Blackjack McCoy has him kidnapped by Indian Joe. Gabe poses as a dangerous gunman, the Klondike Kid, while Slip is in charge of all the remaining loose ends.
Chester Wooley and Duke Egan are travelling salesmen who make a stopover in Wagon Gap, Montana while enroute to California. During the stopover, a notorious criminal is murdered, and the two are charged with the crime.
Slick gambler James Wylie is apprehended by the law and given the option to forgo a prison sentence if he poses as a bandit. His mission is to uncover the identity of the Poet, a notorious outlaw who has been holding up bank-owned stagecoaches and leaving verses at the crime scenes to taunt the authorities. James finds time to woo the Poet's lovely wife, Ann, who initially cold-shoulders him. But, as a romance develops, they partner up to find the robber.
Notorious shootist and womanizer Quirt Evans' horse collapses as he passes a Quaker family's home. Quirt has been wounded, and the kindly family takes him in to nurse him back to health against the advice of others. The handsome Evans quickly attracts the affections of their beautiful daughter, Penelope. He develops an affection for the family and their faith, but his troubled past follows him.
Three brothers stop off for a night in the town of Tombstone. The next morning they find one of their brothers dead and their cattle stolen. They decide to take revenge on the culprits.
In 1850s Oregon, a businessman is torn between his love of two very different women and his loyalty to a compulsive gambler friend who goes over the line.
After some gun play with a posse, the James Gang head for Quinto in a section of land which is not a part of America. Anyone there is beyond the law so the town is populated with outlaws. Next to arrive is Sheriff Rowley, following his brother whom the Gang have brought in injured. Rowley has no authority and gets on well enough with the James boys but is soon involved in other local goings-on, including a move to vote for annexation with Oklahoma which would allow the law well and truly in.
On a train trip out west to become a mail-order bride, Susan Bradley meets a cheery crew of young women traveling out to open a "Harvey House" restaurant at a remote whistle-stop.
Rancher Clay Hardin arrives in San Antonio to search for and capture Roy Stuart, notorious leader of a gang of cattle rustlers. The vicious outlaw is indeed in the Texan town, intent on winning the affections of a beautiful chanteuse named Jeanne Starr. When the lovely lady meets and falls in love with the charismatic Hardin, the stakes for both men become higher.
In 1871, professional gambler John Devlin elopes with Sandra "Sandy" Poli, daughter of Marko Poli, an immigrant who has risen to railroad tycoon. Sandy, knowing that the railroad is to be extended into Dakota, plans to use their $20,000 nest egg to buy land options to sell to the railroad at a profit. On the stage trip to Ft. Abercrombie, their fellow passengers are Jim Bender and Bigtree Collins, who practically own the town of Fargo and Devlin is aware that they are prepared to protect the little empire... trying to drive out the farmers by burning their property, destroying their wheat, and blaming the devastation on the Indians. Continuing their journey north on the river aboard the "River Bird', Sandy and John meet Captain Bounce, an irascible old seafarer. Two of Bendender's henchmen, Slagin and Carp, board the boat and relieve John of his $20,000 at gunpoint. Captain Bounce, chasing the robber's dinghy..
The notorious Dalton Boys have decided to go straight and move to Argentina. Just before they leave, they learn of a friend whose land is about to be seized by a greedy land company. Before they can help, the man is killed by a company assassin. The brothers do manage to rescue his widow and head for the hills. There, they decide to revert back to outlaw life. Meanwhile, a newspaper publisher's daughter falls for one of the brothers.