Holmes, retired to Sussex, is drawn into a last case when his arch enemy Moriarty arranges with an American gang to kill one John Douglas, a country gentleman with a mysterious past. Holmes' methods baffle Watson and Lestrade, but his results astonish them. In a long flashback, the victim's wife tells the story of the sinister Vermissa Valley.
Hard-boiled newspaper reporter Larry Doyle (Robert Armstrong) goes a bit too far in celebrating a work bonus and wakes up on a train bound for St. Louis with only a buck on his person. To remedy the problem, Doyle pawns the revolver he's carrying. When the gun is subsequently used in a murder, Doyle's problems only multiply. In the meantime, he's also fallen in love with a comely stranger (Maxine Doyle) he convinced to impersonate his wife.
A doctor who has spent his career working on ways to revive the dead sees his chance to prove his theory by performing his procedures on a recently deceased dog.
A respected war correspondent is found murdered, with three bullets--from three different guns--in him. Three different men are arrested, convicted and sentenced to death for the murder, but only one can be the actual killer. A criminologist sets out to find who is really guilty.
A valuable gem from India is stolen in an old dark mansion and it is up to Scotland Yard inspector Charles Irwin to find out who did it among all the suspects who were in the house.
After Sheriff Ken puts money in the safe, his brother Clem gives Rawhide the combination. With the money gone the disgruntled townsmen make Boots Sheriff and lock up Ken. Clem, now a prisoner of Rawhide, has a change of heart and sends Ken a message with the outlaw's location. Ken escapes by impersonating the saloon entertainer and rides for the hangout.
When a radio star is found murdered in her home, everyone assumes that the mysterious young woman discovered with her is the culprit — everyone, that is, but newspaper reporter Jerry Beall, who sets out to prove her innocence.
Twelve renegades dressed as Indians kill the parents of two brothers. The brothers who have similar birth marks then separate. Ten years later a man known as the Rawhide Terror is murdering the renegades who are now town citizens. Everyone is after the Rawhide Terror and the two brothers are destined to meet again.
Nora Moran, a young woman with a difficult and tragic past, is sentenced to die for a murder that she did not commit. She could easily reveal the truth and save her own life, if only it would not damage the lives, careers and reputations of those whom she loves.
Philo Vance, accompanied by his prize-losing Scottish terrier, investigates the locked-room murder of a prominent and much-hated collector whose broken Chinese vase provides an important clue.
A man is convicted of killing his boss, whom he suspected of having an affair with his wife. On board the train taking him to prison for his execution are a reporter, who is dying of lung cancer and wants to interview the condemned man--and who also has some inside knowledge of the circumstances of the man's case. Also aboard is the prisoner's wife, who doesn't believe her husband is a killer and desperately wants to talk to him about it but he refuses to speak to her.
In London, a secret society led by lawyer Thaddeus Merrydew collects the assets of any of its deceased members and divides them among the remaining members. Society members start dropping like flies. Sherlock Holmes is approached by member James Murphy's widow, who is miffed at being left penniless by her husband. When Captain Pyke is shot, Holmes keys in on his mysterious Chinese widow as well as the shady Merrydew. Other members keep dying: Malcom Dearing first, then Mr. Baker. There is also an attempt on the life of young Eileen Forrester, who became a reluctant society member upon the death of her father. Holmes' uncanny observations and insights are put to the test.
A handsome radio singer has it all--fame, money, adoring fans--but what no one knows is that his accompanist, a hunchbacked piano player, is actually the voice behind the arrogant, abusive "singer"'s fame. The two men fall for the same girl, and when the singer turns up dead, suspicion falls upon his assistant and the girl.
Four survivors of a ship wreck are stranded on a deserted island, including a woman and the man she believes is responsible for the murder which her brother is in prison for.