Coke Ennyday, the scientific detective, divides his time into periods of "Sleep", "Eat", "Dope" and "Drinks". In fact, he overcomes every situation with drugs: consuming cocaine to increase his energy or injecting it in his opponents to incapacitate them. To help the police, he tracks down a contraband of opium (which he eagerly tastes) transported within "leaping fishes", saving a "fish-blower" girl from blackmail along the way.
A writer, looking for some peace and quiet in order to finish a novel, takes a room at the Baldpate Inn. However, peace and quiet are the last things he gets, as there are some very strange goings-on at the establishment.
The mysterious air pirate Filibus steals from the rich and then retreats to the safety of her airship, which is manned by a staff of mask-wearing lackeys who instantly obey her every command. When an esteemed detective sets out to investigate the thefts, Filibus attempts to frame him as the burglar, while also slipping between male and female disguises to romance the detective's sister.