Glenn Manning, "The Amazing Colossal Man," believed dead after falling from the Hoover Dam, reemerges in rural Mexico, brain damaged, disfigured, and very angry.
An "unknown force" declares war against planet Earth when the United Nations disobeys warnings to cease and desist in its attempts at assembling the first satellite in the atmosphere.
With his assistant, Laura Hutchinson, Dr. David Conway develops a device to advance the fledgling science of earthquake prediction. After forecasting a large trembleor that will rock California within twenty-four hours, Conway cannot persuade the Governor to act. When the prediction proves true and further tests indicate that there are more quakes to come, Conway and Laura seek to perfect their device. Subsequent tests deep within Carlsbad Caverns discover an unknown element—E-112—that is responsible for the earthquakes and threatens to destroy the globe if it ever reaches the surface. The team determines that with only four weeks until Armageddon, the race is on to neutralize the killer element before it takes a devastating toll.
In England, a group of space scientists led by Bernard Quatermass, who have developed plans for the first Moon colony, learn that a secret, ostensibly government-run, complex of identical design has been built in a remote part of England and is the focus of periodic falls of small, hollow "meteorites" originating in outer space. Quatermass determines to investigate and uncovers a terrifying extraterrestrial life form which has already begun action to take over the Earth.
Baron Victor Frankenstein has discovered life's secret and unleashed a blood-curdling chain of events resulting from his creation: a cursed creature with a horrid face — and a tendency to kill.
A test rocket carrying wasps to outer space, to study the effects on them of weightlessness and radiations, crashes out of control back to Earth, into the jungles of Africa. The two astrobiologists in charge of the test mount an expedition to the Darkest Continent to retrieve their experiment, only to find the wasps have grown to giant size which are panicking all forms of life as they quest for food.
A wealthy business man discovers he has a brain tumor and seeks medical help. The business man finds a scientist experimenting with transplanting monkey heads on different monkey bodies. The business man decides to steal the head of Nostradamus from the prophet's crypt.
A dangerous combination of radiation and insecticide causes the unfortunate Scott Carey to shrink, slowly but surely, until he is only a few inches tall. His home becomes a wilderness where he must survive everything from spiders living in the cellar to his beloved cat.
A group of scientists travel to a remote island to study the effects of nuclear weapons tests, only to get stranded when their airplane mysteriously explodes. The team soon discovers that the tests have given rise to crabs mutated into intelligent, impervious, telepathic giants intent on increasing their numbers by breeding, then travelling to populated areas to feed, and which do not intend to be stopped by their discoverers.
When the first manned flight to Venus returns to Earth, the rocket crash-lands in the Mediterranean near a small Italian fishing village. The locals manage to save one of the astronauts Colonel Calder, the mission commander. A young boy also recovers what turns out to be a specimen of an alien creature. Growing at a fantastic rate, it manages to escape and eventually threatens the city of Rome.
Five individuals from five nations, including the USA, USSR, and China, suddenly find themselves on an alien saucer, where an alien gives each a container holding three capsules. The alien explains that no power on earth can open a given container except a mental command from the person to whom it is given, then anyone may take a capsule and, by speaking a latitude and longitude at it, cause instant death to all within a given radius: thus each of the five has been provided with the power of life and death. Then, they are given 27 days to decide whether to use the capsules, and returned to the places from which each one came...
Mining engineer Shigeru investigates the disappearance and death of his fellow coworkers when prehistoric nymphs are discovered emerging from the mines. After an attack on the local village, Shigeru heads deeper into the mines only to make a more horrifying discovery in the form a prehistoric flying creature. Soon a second monster appears as the two converge in Fukuoka.
An American reporter smells a story when he is stranded in an Iron Curtain country where the local dictator is using gamma rays to transform children into mutated henchmen.
In 19th century England, a noted brain surgeon rescues a former student from being hanged on a false conviction for murder, and spirits him away to an ancient, repurposed abbey far in the countryside. There, he connives his pupil into assisting him in mapping the functions of the various parts of the human brain, using living subjects who are under a terrible animation-suspending drug called "black sleep". Subsequently, the student, along with the daughter of one of the subjects, discover that most of these subjects have survived but are being kept in a dungeon-like cellar, in various stages of physical and mental derangement...