In this pilot for a series that was never picked up, Dr. Frankenstein has just finished rebuilding his creation, but the monster is unresponsive. He needs to try something different to make it work, perhaps some new parts. Enter a terminally ill sculptor and his assertive wife…
An evil alien brain, bent on world domination, takes over the body of an atomic scientist, while a "good" alien brain inhabits the body of the scientist's dog and waits for an opportunity to defeat the evil brain.
An attractive reporter investigating the mysterious destruction of an Illinois town stumbles upon a secret government laboratory conducting radiation experiments on vegetables. The lead scientist is eager to help find out what happened. Together they discover that giant grasshoppers are behind the devastation. Worse yet, thousands of them are headed toward Chicago! Can they be stopped... or is this the BEGINNING OF THE END?
A small town doctor mistakenly ingests an experimental drug made from the blood of vampire bats which transforms the kindly medic into a bloodthirsty monster.
With his assistant, Laura Hutchinson, Dr. David Conway develops a device to advance the fledgling science of earthquake prediction. After forecasting a large trembleor that will rock California within twenty-four hours, Conway cannot persuade the Governor to act. When the prediction proves true and further tests indicate that there are more quakes to come, Conway and Laura seek to perfect their device. Subsequent tests deep within Carlsbad Caverns discover an unknown element—E-112—that is responsible for the earthquakes and threatens to destroy the globe if it ever reaches the surface. The team determines that with only four weeks until Armageddon, the race is on to neutralize the killer element before it takes a devastating toll.
In England, a group of space scientists led by Bernard Quatermass, who have developed plans for the first Moon colony, learn that a secret, ostensibly government-run, complex of identical design has been built in a remote part of England and is the focus of periodic falls of small, hollow "meteorites" originating in outer space. Quatermass determines to investigate and uncovers a terrifying extraterrestrial life form which has already begun action to take over the Earth.
Baron Victor Frankenstein has discovered life's secret and unleashed a blood-curdling chain of events resulting from his creation: a cursed creature with a horrid face — and a tendency to kill.
A test rocket carrying wasps to outer space, to study the effects on them of weightlessness and radiations, crashes out of control back to Earth, into the jungles of Africa. The two astrobiologists in charge of the test mount an expedition to the Darkest Continent to retrieve their experiment, only to find the wasps have grown to giant size which are panicking all forms of life as they quest for food.
A wealthy business man discovers he has a brain tumor and seeks medical help. The business man finds a scientist experimenting with transplanting monkey heads on different monkey bodies. The business man decides to steal the head of Nostradamus from the prophet's crypt.
Deep in the jungles a mad scientist is using the natives' voodoo for his experiments to create an indestructible being to serve his will. When a party of gold seekers stumbles upon his village, the scientist realizes that Marilyn the expedition's evil leader is the perfect subject for his work.
A dangerous combination of radiation and insecticide causes the unfortunate Scott Carey to shrink, slowly but surely, until he is only a few inches tall. His home becomes a wilderness where he must survive everything from spiders living in the cellar to his beloved cat.
An alien from planet Davanna, whose population has developed a terminal blood disease caused by nuclear radiation, is sent to Earth to acquire fresh human blood for his people.
A group of scientists travel to a remote island to study the effects of nuclear weapons tests, only to get stranded when their airplane mysteriously explodes. The team soon discovers that the tests have given rise to crabs mutated into intelligent, impervious, telepathic giants intent on increasing their numbers by breeding, then travelling to populated areas to feed, and which do not intend to be stopped by their discoverers.