Poor Red Jones gets fired from every job he tries. His fiancée gives him one last chance to make good when he becomes a Fuller Brush man. His awkward attempts at sales are further complicated when one of his customers is murdered and he becomes the prime suspect.
A gang of criminals, which includes a piano player and an imposing former convict known as 'Gruesome', has found out about a scientist's secret formula for a gas that temporarily paralyzes anyone who breathes it. When Gruesome accidentally inhales some of the gas and passes out, the police think he is dead and take him to the morgue, where he later revives and escapes. This puzzling incident attracts the interest of Dick Tracy, and when the criminals later use the gas to rob a bank, Tracy realizes that he must devote his entire attention to stopping them.
Up-and-coming Hollywood actor/crooner, Vic Morton, has a secret. He starts receiving death threats in the mail and an attempt on his life is made. Soon after, two of his associates are murdered. Who is behind it all?
Dick Tracy investigates the theft of a fortune of fur coats, a possible insurance swindle and several murders, all linked to a huge thug who wears a hook in place of his right hand.
Art editor Madeleine Damian carries on numerous loveless affairs. After a failed relationship with advertiser Felix Courtland, the increasingly depressed Madeleine attempts suicide. When Jack Garet, her secretary and former lover, tries to blackmail her, Madeleine resigns and seeks a reclusive life. Neighbor David Cousins befriends Madeleine, but soon Courtland and Garet discover her whereabouts and disrupt her new life.
The dream is unusually vivid: Bank employee Vince Grayson finds himself murdering a man in a sinister octagonal-shaped room lined with mirrors while a mysterious woman breaks into a safe. It is so vivid that Vince suspects it may have really happened. To get the dream off his mind, he goes on a picnic with some relatives. When a thunderstorm forces his party into a nearby mansion, Vince discovers that the bizarre room does exist, and it means nothing but trouble.
In a series of flashbacks, shows that attorney John Morland has given a lift to a hitchhiker who turns out to be a murderer. As a result, Morland himself is implicated in a killing. A pair of detectives discover that Morland has been having business problems and no end of difficulties with his wife Catherine. The trail of clues leads to a surprising revelation.
War heroes Rip Murdock and Johnny Drake are sent to Washington, D.C, to receive top honors for their service. Johnny, seemingly terrified by the publicity that awaits him, jumps off the train and later turns up dead. Suspecting foul play, Rip begins digging into his pal's past. He encounters cover-ups, threats to his own life and deadly femme fatale Coral Chandler.
Rancher "Utah" Neyes crosses the border into Canada to meet his partner, only to find that the latter has been murdered by a gang led by "Nails" Nelson. "Utah", with the aid of RCMP Jack Craig and fur-trapper Ivy Jenkins, manages to clear his own name of suspicion and also break up Nelson's fur-stealing and smuggling racket.
An investigator from the War Crimes Commission travels to Connecticut to find an infamous Nazi, who may be hiding out in a small town in the guise of a distinguished professor engaged to the Supreme Court Justice’s daughter.
A convicted thief in Dartmoor prison hides the location of the stolen Bank of England printing plates inside three music boxes. When the innocent purchasers of the boxes start to be murdered, Holmes and Watson investigate.
Holmes and Watson board a passenger train bound from London to Edinburgh, to guard the Star of Rhodesia, an enormous diamond worth a fortune belonging to an elderly woman of wealth; but within the first hour of the trip, the woman's son is murdered and the diamond stolen and any of the passengers in their car could be the killer thief.
When beautiful Mary returns to her "whistle stop" hometown, long-standing feelings of animosity between two of her old boyfriends leads to robbery and murder.
Cashier and part-time starving artist Christopher Cross is absolutely smitten with the beautiful Kitty March. Kitty plays along, but she's really only interested in Johnny, a two-bit crook. When Kitty and Johnny find out that art dealers are interested in Chris's work, they con him into letting Kitty take credit for the paintings. Cross allows it because he is in love with Kitty, but his love will only let her get away with so much.