Young lovers Jack and Sally are from families that compete to send horses to the 1938 Kentucky Derby, but during the Civil War, her family sided with the South while his sided with the North--and her Uncle Peter will have nothing to do with Jack's family.
Heiress Nancy Crocker Fleming will only receive her inheritance if she marries a "plain American." Her late father was afraid a foreign gigolo would steal her heart and money. So Nancy pays Tony Anthony, working on a WPA road project, to marry, then divorce her. When Nancy inadvertently drives off with Tony's dog, Tony seemingly kidnaps her to retrieve the pooch, which leads to a cross-country race between the two to reach Reno and the divorce court since neither one wants to be the second to file papers.
Andrew Manson, a young, idealistic, newly qualified Scottish doctor arrives in Wales takes his first job in a mining town, and begins to wonder at the persistent cough many of the miners have. When his attempts to prove its cause are thwarted, he moves to London. His new practice does badly. But when a friend shows him how to make a lucrative practice from rich hypochondriacs, it will take a great shock to show him what the truth of being a doctor really is.
To stop Pinkie's widowed, struggling mother Dottie from marrying a well-off older man they know she doesn't love, teenager Pinkie and her best friend Buzz kidnap her in the family travel trailer to live a carefree life on the open road. They then get the idea to find Dottie a financially secure husband whom both she and Pinkie would like.
While in Shanghai reporting on the Sino-Japanese war, Chris Hunter, a shrewd news reporter, meets pilot Alma Harding. She does not trust him, but he manages to hire her as his assistant. During an adventurous expedition through the jungles of South America, her opinion of him begins to change.
Alice, the only relatively normal member of the eccentric Sycamore family, falls in love with Tony Kirby, but his wealthy banker father and snobbish mother strongly disapprove of the match. When the Kirbys are invited to dinner to become better acquainted with their future in-laws, things don't turn out the way Alice had hoped.
During WWI Bill Pettigrew, a naive young Texan soldier is sent to New York for basic training. He meets worldly wise actress Daisy Heath when her car nearly runs him over.
Johnny Case, a freethinking financier, has finally found the girl of his dreams — Julia Seton, the spoiled daughter of a socially prominent millionaire — and she's agreed to marry him. But when Johnny plans a holiday for the two to enjoy life while they are still young, his fiancée has other plans & that is for Johnny to work in her father's bank!
American multi-millionaire Michael Brandon marries his eighth wife, Nicole, the daughter of a broke French Marquis. But she doesn't want to be only a number in the line of his ex-wives and undertakes her own strategy to tame him.
David Huxley is waiting to get a bone he needs for his museum collection. Through a series of strange circumstances, he meets Susan Vance, and the duo have a series of misadventures which include a leopard called Baby.
Jessie, a young working class woman, seeks to improve her life by marrying her boyfriend, only to find out that he is no better than what she left behind.
After losing a coveted role in an upcoming film to another actress, screen queen Mona Marshall (Lola Lane) protests by refusing to appear at her current movie's premiere. Her agent discovers struggling actress Virginia Stanton (Rosemary Lane) -- an exact match for Mona -- and sends her to the premiere instead, with young musician Ronnie Bowers (Dick Powell). After various mishaps, including a case of mistaken identity, Ronnie and Virginia struggle to find success in Hollywood.