When honest ship captain Roy Glennister gets swindled out of his mine claim, he turns to saloon singer Cherry Malotte for assistance in his battle with no-good town kingpin Alexander McNamara.
Boston pharmacist Tom Craig comes to Sacramento, where he runs afoul of local political boss Britt Dawson, who exacts protection payment from the citizenry. Dawson frames Craig with poisoned medicine, but Craig redeems himself during a Gold Rush epidemic.
The story follows General George Armstrong Custer's adventures from his West Point days to his death. He defies orders during the Civil War, trains the 7th Cavalry, appeases Chief Crazy Horse and later engages in bloody battle with the Sioux nation.
Two peanut vendors at a rodeo show get in trouble with their boss and hide out on a railroad train heading west. They get jobs as cowboys on a dude ranch, despite the fact that neither of them knows anything about cowboys, horses, or anything else.
Fast-talking con-man and grifter Candy Johnson rises to be the corrupt boss of Yellow Creek, but his wife's alcoholic father tries to set things right.
Billy Bonney is a hot-headed gunslinger who narrowly skirts a life of crime by being befriended and hired by a peaceful rancher, Eric Keating. When Keating is killed, Billy seeks revenge on the men who killed him, even if it means opposing his friend, Marshal Jim Sherwood.
When Edward Creighton leads the construction of the Western Union to unite East with West, he hires a Western reformed outlaw and a tenderfoot Eastern surveyor. Preserved by the Academy Film Archive in partnership with Twentieth Century Fox Film Corporation in 2000.
Elliott is hunted by Curtis who has spent six years behind bars because of his testimony. After knocking out several baddies and putting up with the zany antics of his sidekick Taylor, Elliott guns down his antagonist, but Luana Walters, the girl he almost marries, will not abide a gunslinger so Elliott is compelled to ride off alone into the sunset once more.
Phoebe Titus is a tough, swaggering pioneer woman, but her ways become decidedly more feminine when she falls for California bound Peter Muncie. But Peter won't be distracted from his journey and Phoebe is left alone and plenty busy with villains Jefferson Carteret and Lazarus Ward plotting at every turn to destroy her freighting company. She has not seen the last of Peter, however.
As a penalty for fighting fellow classmates days before graduating from West Point, J.E.B. Stuart, George Armstrong Custer and four friends are assigned to the 2nd Cavalry, stationed at Fort Leavenworth. While there they aid in the capture and execution of the abolitionist, John Brown following the Battle of Harper's Ferry.
Embezzler, shill, all around confidence man S. Quentin Quale is heading west to find his fortune; he meets the crafty but simple brothers Joseph and Rusty Panello in a train station, where they steal all his money. They're heading west, too, because they've heard you can just pick the gold off the ground. Once there, they befriend an old miner named Dan Wilson whose property, Dead Man's Gulch, has no gold. They loan him their last ten dollars so he can go start life anew, and for collateral, he gives them the deed to the Gulch. Unbeknownst to Wilson, the son of his longtime rival, Terry Turner (who's also in love with his daughter, Eva), has contacted the railroad to arrange for them to build through the land, making the old man rich and hopefully resolving the feud. But the evil Red Baxter, owner of a saloon, tricks the boys out of the deed, and it's up to them - as well as Quale, who naturally finds his way out west anyway - to save the day.
Trouble in Colorado is tying up Union troops needed back east during the Civil War and Lieut. Burke is sent to investigate. Macklin and his gang are causing the problems and Capt. Mason joins them. When Burke catches up with them he also finds Mason, his brother.
Two buddies who rise from fly-by-night wildcatters to oil tycoons over a twenty year period both love the same woman. McMasters and Sand come to oil towns to get rich. Betsy comes West intending to marry Sand but marries McMasters instead. Getting rich and losing it all teaches McMasters and Sand the value of personal ties.
Young lawyer Tod Jackson arrives in pioneer Kansas to visit his prosperous rancher friends the Daltons, just as the latter are in danger of losing their land to a crooked development company. When Tod tries to help them, a faked murder charge turns the Daltons into outlaws, but more victims than villains in this fictionalized version. Will Tod stay loyal to his friends despite falling in love with Bob Dalton's former fiancée Julie?
The Durango Kid is a sort of Robin Hood of the West who helps the lovely Walters (who replaced Starrett's usual love-interest, Iris Meredith), the daughter of a homesteader, defeat the evil MacDonald who has been terrorizing the decent citizens with his gang of rustlers.