The famous Borgia Pearl, a valuable gem with a history of bringing murder and misfortune to its owner since the days of the Borgias, is brought to London, thanks in part to Sherlock Holmes. But before long the jewel is stolen, due to an error on Holmes' part, and shortly thereafter, a series of horrible murders begin, the murderer leaving his victims with their spines snapped and surrounded by a mass of smashed china.
When a woman is found dead with her throat torn out, the local villagers blame a supernatural monster. But Sherlock Holmes, who gets drawn into the case from nearby Quebec, suspects a human murderer.
Convinced that she has what it takes to be a detective, inquisitive secretary Kitty O'Day gets her chance to put her sleuthing skills to the test when her investment broker boss is mysteriously murdered. But Kitty's investigation hits a snag when Inspector Miles Clancy begins to suspect that she's the culprit.
When a treasure hunter seeks a downed airplane in the jungles of Africa, he encounters one of the passenger's young daughter, now fully grown, and with a gorilla protector.
Sherlock Holmes investigates a series of so-called "pajama suicides". He knows the female villain behind them is as cunning as Moriarty and as venomous as a spider. Based on "The Sign of Four" and the short stories "The Dying Detective", "The Final Problem", "The Speckled Band" and "The Adventure of the Devil's Foot".
During WWII several murders occur at a convalescent home where Dr. Watson has volunteered his services. He summons Holmes for help and the master detective proceeds to solve the crime from a long list of suspects including the owners of the home, the staff and the patients recovering there.
One dark and stormy night, an escaped convict, an embezzler, a runaway daughter, her intended and her father, and a gangster take refuge in a remote inn called "The Black Raven" after the nickname of a second gangster who owns it; and murder ensues.
After one member of their group is murdered, the performers at a burlesque house must work together to find out who the killer is before they strike again.
Newlyweds Webster and Jackie Frye spend their honeymoon in a sinister old country house. Before long, they are besieged by a gang of crooks, searching for a fortune in diamonds. With the help of chauffeur Harmony Jones, the honeymooners attempt to outsmart the villains.
When a small town doctor buries his twin brother, a practitioner of the black arts, he believes him dead; but subsequent events force him to realize that his brother has, in fact, returned from the dead as a vampire and is seeking revenge on the doctor, who had killed him in self-defense.
In World War II, a British secret agent carrying a vitally important document is kidnapped en route to Washington. The British government calls on Sherlock Holmes to recover it.
In the midst of World War II, Sherlock Holmes rescues the Swiss inventor of a new bomb-sight from the Gestapo and brings him to England, where he quickly falls into the clutches of the evil Professor Moriarty.
The police arrest a man climbing over the wall of a cemetery after midnight. He claims that he is being blackmailed and is following instructions he received by mail to leave $1000 on a certain grave. It turns out that he's not the only one who got a blackmail letter from the same person--calling himself "The Black Panther"--and it also turns out that all the recipients are connected to an opera company.
Topper is once again tormented by a fun-loving spirit. This time, it's Gail Richards, accidentally murdered while vacationing at the home of her wealthy friend, Ann Carrington, the intended victim. With Topper's help, Gail sets out to find her killer with the expected zany results.