Edited version of The Lawless Frontier. Mexican outlaw Zanti killed John Tobin's parents. John teams up with Dusty, also hurt by Zanti, to get the bad guy.
A ranch hand sets out to prove his father is innocent of murder in this B-movie Western starring cowboy hero Tom Tyler. Disguised as an outlaw, Tom Lansing (Tyler) takes up with a motley crew hiding out in a ghost town to catch the true killer. This 1934 classic co-stars Frank Rice as Lansing's sidekick, Banty, and Roberta Gale as Bess, a beautiful young captive of the outlaw gang who is in desperate need of a hero.
Tobin is after the bandit Zanti who killed his parents. He finds him just as Zanti is about to kill Dusty and kidnap Ruby. Saving the two, he goes after Zanti. He catches him but Zanti escapes the Sheriff's handcuff's and this time Tobin has to chase him into the desert.
Gangster Chandler and his accomplice Tracy arrive at a dude ranch. Cowboy Kentucky arrives at the same time. When Tracy double-crosses his boss and has the stage robbed, Kentucky finds the outlaws and brings them in. Tracy frames him for the murder of the driver but his pal Cactus gets him out of jail. He returns just as Chandler shoots Tracy and Kentucky finds himself arrested for another murder.
Henry Jethrow is after the Wilson ranch. He has George Wilson unknowningly sign a note for the ranch, has him killed, and then presents the note. The Pinto Kid, investigating cattle rustlers, accidentally drops his glove at the murder scene and now has a price on his head. He has Beth Wilson turn him and use the reward money to reclaim the note. Now he has to escape jail and find the real killers.
Trouble starts when Bill Larkins and his two sons move in with his brother Joe. They start rustling cattle and then kill Rod's father with Joe's gun. The Sheriff and Rod think they did it and are after proof.
Big-city gangsters run out of gas in the middle of the desert. A local cowboy gives them a tow back to his ranch, and the gangsters decide his ranch would be the perfect hide-out.
When the Ranger Sergeant returns murdered with a note that LaFarge did it, Trooper Burke sets out to after LaFarge. Working undercover, he saves LaFarge's life and this gets him into LaFarge's gang. He then arrests LaFarge and brings him in only to learn that LaFarge is not only innocent but is now a prisoner of the real killer.
A cowboy tries to protect a young woman whose father was murdered because he had railroad maps that showed the location of a proposed new line. Now the killers are after her because they think she has the maps.
Government agent Gordon, working undercover, is investigating a cattleman sheepman war. The Culprit is Horton and when Horton kills Parker he frames Gordon. His identity revealed, the Sheriff lets Gordon escape to go after the real killer.
Rocky Rhodes returns to find his father dead and his best friend Joe accused of the murder. The culprit is Murtch who now lets Joe break jail and then has him shot escaping. When Rocky starts to interfere with Murtch's plans, he has Rocky framed for murder. Rocky now has to prove Murtch is guilty while escaping the law.
An Easterner Inherits a cattle ranch, only to discover that thousands of cattle have been stolen. He secretly signs on as a hired hand at his own ranch to discover who's stealing them.
A wagon train heads west from Independence, Mo., along the Oregon Trail, led by proud cowboy Clint Belmet. On board are feisty young widow Nancy Wellington and her toddler, Sonny, as well as the older Abby Masters, who begins a romance with scout Jim Burch. Along the way, the wagon train battles Indians led by Kenneth Murdock, a trapper who doesn't welcome competition for Oregon's lucrative fur trade. Wagon Wheels is a 1934 remake of 1931's Fighting Caravans, using stock footage from the original.