A huge, alien structure resembling an inverted cone, appears in the woods outside a small rural town. Sent from Washington to investigate the origin of the mysterious object, a team of investigators discovers that intelligent parasites from inside the "cone" can attach themselves to humans' nervous systems and control their minds, taking control of the authorities and workers, making communication with the outside world impossible, and leaving the responsibility of stopping the invasion up to seven people who have thus far been able to avoid possession by these creatures from parts unknown.
Teenagers from a small town and their high school science teacher join forces to battle a giant mutant spider, living in a cave nearby and getting hungry.
After exposure to radiation, an atomic research scientist finds himself changing into a murderous, lizard-like creature every time he is exposed to sunlight.
A man and wife are terrorized by Mad Scientist Dr. Callistratus who was executed but has returned to life with a heart transplant. Along with his crippled assistant Carl, the 'anemic' Mad Scientist, believed to be a vampire, conducts blood deficiency research on the inmates of a prison hospital for the criminally insane to sustain his return to life.
An astronaut returns to Earth as the no-pulse host of an alien monster's embryos; he is discovered by a loony farmer who find ways to feed his new critter.
Glenn Manning, "The Amazing Colossal Man," believed dead after falling from the Hoover Dam, reemerges in rural Mexico, brain damaged, disfigured, and very angry.
An "unknown force" declares war against planet Earth when the United Nations disobeys warnings to cease and desist in its attempts at assembling the first satellite in the atmosphere.
A small town doctor mistakenly ingests an experimental drug made from the blood of vampire bats which transforms the kindly medic into a bloodthirsty monster.
Global panic ensues when it is revealed that a mysterious UFO is actually a giant turkey-like bird that flies at supersonic speed and has no regard for life or architecture.
In England, a group of space scientists led by Bernard Quatermass, who have developed plans for the first Moon colony, learn that a secret, ostensibly government-run, complex of identical design has been built in a remote part of England and is the focus of periodic falls of small, hollow "meteorites" originating in outer space. Quatermass determines to investigate and uncovers a terrifying extraterrestrial life form which has already begun action to take over the Earth.
A test rocket carrying wasps to outer space, to study the effects on them of weightlessness and radiations, crashes out of control back to Earth, into the jungles of Africa. The two astrobiologists in charge of the test mount an expedition to the Darkest Continent to retrieve their experiment, only to find the wasps have grown to giant size which are panicking all forms of life as they quest for food.
A wealthy business man discovers he has a brain tumor and seeks medical help. The business man finds a scientist experimenting with transplanting monkey heads on different monkey bodies. The business man decides to steal the head of Nostradamus from the prophet's crypt.
Deep in the jungles a mad scientist is using the natives' voodoo for his experiments to create an indestructible being to serve his will. When a party of gold seekers stumbles upon his village, the scientist realizes that Marilyn the expedition's evil leader is the perfect subject for his work.