A gang of criminals, which includes a piano player and an imposing former convict known as 'Gruesome', has found out about a scientist's secret formula for a gas that temporarily paralyzes anyone who breathes it. When Gruesome accidentally inhales some of the gas and passes out, the police think he is dead and take him to the morgue, where he later revives and escapes. This puzzling incident attracts the interest of Dick Tracy, and when the criminals later use the gas to rob a bank, Tracy realizes that he must devote his entire attention to stopping them.
Sandra Carpenter is a London-based dancer who is distraught to learn that her friend has disappeared. Soon after the disappearance, she's approached by Harley Temple, a police investigator who believes her friend has been murdered by a serial killer who uses personal ads to find his victims. Temple hatches a plan to catch the killer using Sandra as bait, and Sandra agrees to help.
The dream is unusually vivid: Bank employee Vince Grayson finds himself murdering a man in a sinister octagonal-shaped room lined with mirrors while a mysterious woman breaks into a safe. It is so vivid that Vince suspects it may have really happened. To get the dream off his mind, he goes on a picnic with some relatives. When a thunderstorm forces his party into a nearby mansion, Vince discovers that the bizarre room does exist, and it means nothing but trouble.
An old man and his sister are concealing a terrible secret from their adopted teen daughter, concerning a hidden abandoned farmhouse, located deep in the woods.
A woman is married to the son of a doctor, the proprietor of a private sanatorium, where she is under unwilling treatment. Both the son and the doctor indicate they want the marriage dissolved. Arriving at the scene is a mysterious personage identified as the doctor's cousin who formerly was a stage magician in Europe. He is accompanied by a threatening dwarf.
Three childhood friends, Martha, Walter and Sam, share a terrible secret. Over time, the ambitious Martha and the pusillanimous Walter have married. She is a cold businesswoman; he is the district attorney: a perfect combination to dominate the corrupt city of Iverstown at will. But the unexpected return of Sam, after years of absence, deeply disturbs the life of the odd couple.
An investigator from the War Crimes Commission travels to Connecticut to find an infamous Nazi, who may be hiding out in a small town in the guise of a distinguished professor engaged to the Supreme Court Justice’s daughter.
After three men are convicted of bank robberies, Charlie becomes suspicious. After some investigation Charlie finds the men are innocent and that the fingerprint evidence used to convict them had been forged. Charlie then proceeds to find the true bank robbers.
A convicted thief in Dartmoor prison hides the location of the stolen Bank of England printing plates inside three music boxes. When the innocent purchasers of the boxes start to be murdered, Holmes and Watson investigate.