Rancher Reynolds has fired his men and hired killers and is now using a crooked land deal to put the other ranchers off their land. Calico finds the reason why when he runs into his old nemesis Porter.
Cattlemen's Protective Association agent Tom Wade and his partner Happy are assigned to look into the disappearance of rancher John Carroll, who has been abducted by Carson, who wants to use his out-of-the-way ranch as a base for his smuggling operations. Complications arise as Carrol's daughter, Rita, looking for him, has an unfriendly run-in with Wade, then later is herself kidnapped by Carson.
Young Dave Austin hunts down the varmint who murdered his father in this B Western. Austin tracks killer Jim Hatfield to his hideout, a Mexican cantina where Hatfield and his ruthless gang terrorize the locals. After being deputized, the courageous Austin allows himself to be captured by the gang and devises an ingenious plan to turn the bad guys against one another.
"Nevada" and "Weary" Pierce hijack the loot taken in a bank hold-up by Les Setter, and his gang. They escape from Sheriff Jim Henry Warner. U. S. government horse-buyer David Ward is killed by Settler's men and Settler takes his papers and goes to the ranch of Blaine and asks for the horses Ward was to buy, promising payment from the government later. He also takes an interest in Ina Blaine, much to the resentment of her sweetheart Ben Ide. "Nevada" and "Weary" are hired for the horse round-up but Setter has them and Ben arrested on a fake charge.
Tex and his pals join the Rangers to fight rustlers along the border. When Doc and Pee Wee get framed for rustling and then jailed, Tex deserts the Rangers, crosses the border, and joins up with the outlaw gang hoping somehow to clear his pals.
Stony's brother George has been accused of murder and the Mesquiteers have returned to prove his innocence. But they find that Harvey rules the town along with his stooge Sheriff Gray and that George won't get a fair trial.
Tyler is a range detective whose brother stands accused of robbing a bank and murdering the bank president. To prove him innocent, Tyler must decipher his only clue, an unusual set of tire tracks.
Deputies Gene Autry and Frog go up against modern cattle rustlers. These rustlers use technology such as, airplanes, radios and refrigerated trucks to steal the cows, butcher them in the field and ship them out before getting caught. This causes the town to bring in a modern NYC detective to catch the crooks, but will Autry and Frog be permanently out of a job?
Cowboy Larry O'Day and his sidekick Lucky Smith happen upon a distraught Barbara Hartwell, who is about to be arrested for the murder of her uncle. With Barbara behind bars, Larry is determined to find the real killer and soon finds himself in the middle of a mystery involving crazed German entomologists and a smuggling ring bringing Chinese "picture girls" across the Mexican border for sale to wealthy Chinese bachelors.
American federal agent Clark Stuart is on assignment in Santa Fe to draw up a trade agreement with the newly installed Mexican governor. Meanwhile, Walter Jamison leads a wagon train from Missouri, hoping to take advantage of the new agreement. Among Jamison's passenger are famed frontiersman Jim Bowie and a very youthful Kit Carson. The destinies of all these personalities intersect when villainous ex-governor DuPrey schemes to undermine the treaty and take over the New Mexico territory for his own vile purposes. Somewhere along the way, Davy Crockett joins the "good guys" in their efforts to thwart the despicable DuPrey.
Shortly after Brand kills Gelbert, Tom Rayburn arrives on the scene and is accused of the murder. Escaping, he goes after Doc Mathews, the man that can prove his innocence. Brand is also after Mathews and intends to keep him from testifying. But Mathews is a ventriloquist and this will lead to Brand's downfall.
Harris and Rigby own a circus. Rigby is a counterfeiter and frames his partner. The Mesquiteers learn Rigby is the culprit and get a confession from one of his men only to lose the case when the man is murdered in jail. The Mesquiteers try again and send Lullaby to try and win some of the fake bills in a card game.
Kalmus is after the freight contract held by Summers. When his gang kill Summers, Tex and Duke step in to help Madge keep the freight line going. When they foil the gang's further attempts, Kalmus gets the Judge to jail the two.
Lawyer Bowdre has started a war between the ranchers and the homesteaders planning to take over the homesteaders land when they are wiped out. Rancher Dan Stockton, having just married homesteader Gail Dawson, is caught in the middle. He suspects Bowdre is behind the war and it's not long before he gets a chance to prove it.
When Johnny and Mendez argue, the lights go out, and in the ensuing gunfight Johnny thinks he killed his friend Dick. Now refusing to wear a gun he crosses the border. But it is not long before he runs into Mendez and more trouble.
Gene and Frog, out to stop a bunch of cattle rustlers, assume the identities of what they believe to be dead bandits, which soon gets them in big trouble.