Ben Hall offers $1000 for the wild Devil Horse which Jim Wright and Skeeter capture. While Jim is away, Gil Davis kills Skeeter and takes the horse. The Sheriff then arrests Jim for Skeeter's murder. But unknown to them, an outlaw witnessed the killing
When the Nevada Kid gets caught in a stage robbery, the gang leader Cherokee gets him released by forging a petition to the Governor. The Kid tries to go straight but the stage he is guarding gets robbed. When the Sheriff jails Cherokee who was not in on the robbery, the Kid gets caught effecting Cherokee's escape and finds himself in jail again.
Marshals Blackie and Joe, posing as two-gun men, hire on at Markham's ranch. They are after Tulliver and his gang of rustlers. But unknown to the two, Tulliver has planted Thorn on the ranch and he kills the foreman Riggs and puts the blame on Blackie.
Blackie Saunders and his young partner Sandy arrive in Indian Springs where Blackie meets his old friend Jim whom he once rode with on the wrong side of the law. Jim is now the Parson but Blackie still carries the reputation of a killer. When the townspeople decide Blackie is not a fit guardian for the boy, Jim convinces Blackie to leave the boy with him. But just after Blackie leaves town, the express office is robbed and it is assumed Blackie did it.
Clint Belmet (Gary Cooper) is a bit of a firebrand and is sentenced to at least 30 days in jail, but his partners, Bill Jackson (Ernest Torrence) and Jim Bridger (Tully Marshall) talk a sympathetic Frenchwoman named Felice (Lili Damita) into telling the bumbling, drunken marshal that Clint had married her the previous night. Clint is released so he can accompany Felice on the wagon train heading west to California.
Western pardners Jeff and Cash find a baby boy in an otherwise deserted emigrants' camp, and clash over which is to be "father." They are still bitterly feuding years later when they own adjacent ranches. Bill, the foundling whom Cash has raised to young manhood, wants to end the feud and extends an olive branch toward Jeff, who now has a lovely daughter. But during a mining venture, the bitterness escalates. Is Bill to be set against his own adoptive father?
El Malo, notorious Mexican bandit, forces the Mayor of Sierra Blanca, Seth Landport, to open the safe and turn over to him 2,000 pesos, which the bandit gives a promissory note for to the Mayor. Seth rushes to the cantina where Sheriff Rankin is drinking, and the sheriff posts a reward for the capture of El Malo. El Malo informs his men of the reward. The bandit and his sidekick, Pedro, visit the cantina where Pedro resumes a former acquaintance with Dolores, while El Malo has his attention directed to a tango being performed by Carmita. El Malo pushes her dancing partner aside and finishes the dance with Carmita. Since Seth's description of him is not accurate, El May visits the sheriff and promises to deliver the wanted bandit to the cantina the following night. THe following morning, El Malo and Pedro depart, and, halting their horses on a hill, view the stagecoach being held up by a trio of outlaws.
After Bob Lansing (Jay Wilsey as Buffalo Bill Jr). is involved in a nightclub scrape, where he meets Montana rancher Madge Holt (Allene Ray)), his father sends him out west with his chauffeur Ben (Ben Corbett). In Montana, they are mistaken for rustlers Dick (Tom London) and Jim (Yakima Canutt), and Bob again meets Madge, who recognizes him but wishes to make things difficult for him.
Having helped his father escape the law, Jim Curtis heads north with the Marshal chasing him. He and his pal Snicker elude the Marshall by changing clothes with two actors. Now forced to do vaudeville skits, Jim finds the man responsible for his and his father's problem working in the same saloon.
Young scout Breck Coleman leads a wagon train along the dangerous trail to Oregon as he tries to get the affection of the beautiful pioneer Ruth Cameron and plans his revenge on the harsh scoundrels who murdered a friend of his in the past.
Western sheriff Bob Wells is preparing to marry Sally Morgan; she loves part-Indian Wanenis, whose race is an obstacle. Sally flees the wedding with hypochondriac Henry Williams, who thinks he's just giving her a ride; but she left a note saying they've eloped! Chasing them are jilted Bob, Henry's nurse Mary (who's been trying to seduce him) and others.
Using a false accusation of unlawful land-squatting, Bill Edwards (Al Ferguson) goes to the County Seat and has Sheriff Brown to swear out a warrant against sheep-herders Marie Valerian (Neva Gerber) and her father (Silver Tip Baker. The Sheriff sends a Deputy, "Thundering" Thompson (Cheyenne Bill_, back to serve the warrant. Thompson learns that Edwards is only trying to force the Valerians to sell their sheep to him at a cheap price, and comes back without serving the warrant. This enrages Edwards who enlists the aid of a local cattleman and his hands to drive off the sheep. Thompson sets out to keep this from happening.
Stephen Ghent, a mineowner, falls in love with Ruth Jordan, an arrogant girl from the East, unaware that she is the daughter of his dead partner. Ruth is vacationing in Arizona and Mexico with a fast set of friends, including her fiancé, Edgar. Manuella, a Spanish halfbreed hopelessly in love with Ghent, causes Ruth to return to her fiancé when she insinuates that Ghent belongs to her. Ghent follows Ruth, kidnaps her, and takes her into the wilderness to endure hardship. There she discovers that she loves Ghent, and she discards Edgar in favor of him.
In a cantina across the border, Bob Hamlin shoots a man that threatens his friend. He and his pals escape but return that night for the dance as Bob is attracted to Conchita. Running once more from the Rurales, Bob takes Conchita. They escape again only to find themselves pinned down when Buck and his gang of horse thieves attack.