Lulu is a young woman so beautiful and alluring that few can resist her siren charms. The men drawn into her web include respectable newspaper publisher Dr. Ludwig Schön, his musical producer son Alwa, circus performer Rodrigo Quast, and seedy old Schigolch. When Lulu's charms inevitably lead to tragedy, the downward spiral encompasses them all.
Jean and Marise, young lovers forced from their homes, flee to Paris. Irrevocably separated there, their lives deviate into the slums and hard labor of low-class French society. All the while, the two desperately search for one another.
Francis, a young man, recalls in his memory the horrible experiences he and his fiancée Jane recently went through. Francis and his friend Alan visit The Cabinet of Dr. Caligari, an exhibit where the mysterious doctor shows the somnambulist Cesare, and awakens him for some moments from his death-like sleep.