Twenty years removed from Alice Barlow's murder by a thief looking for her jewels, newlyweds Paul and Bella Mallen move into the very house where the crime was committed. Retired detective B.G. Rough, who worked on the Barlow case, is still in the area and grows suspicious of Paul, who he feels bears a striking resemblance to one of Barlow's relatives. Rough must find the truth before the killer can strike again and reclaim his bounty.
American crime reporter John Jones is reassigned to Europe as a foreign correspondent to cover the imminent war. When he walks into the middle of an assassination and stumbles on a spy ring, he seeks help from a beautiful politician’s daughter and an urbane English journalist to uncover the truth.
Joe and Paul Fabrini are Wildcat, or independent, truck drivers who have their own small one-truck business. The Fabrini boys constantly battle distributors, rivals and loan collectors, while trying to make a success of their transport company.
In 1828, the bankrupt Pyncheon family fight over Seven Gables, the ancestral mansion. To obtain the house, Jaffrey Pyncheon obtains his brother Clifford's false conviction for murder. Hepzibah, Clifford's sweet fiancée, patiently waits twenty years for his release, whereupon Clifford and his former cellmate, abolitionist Matthew, have a certain scheme in mind.
After World War I, Armistice Lloyd Hart goes back to practice law, former saloon keeper George Hally turns to bootlegging, and out-of-work Eddie Bartlett becomes a cab driver. Eddie builds a fleet of cabs through delivery of bootleg liquor and hires Lloyd as his lawyer. George becomes Eddie's partner and the rackets flourish until love and rivalry interfere.
Having once again avoided criminal conviction, Professor Moriarity develops a murderous plan to “finish off” his last major nemesis, Sherlock Holmes, by making him fail to prevent the perfect crime. Does it involve a family curse, the crown jewels of England, or something else…
A corrupt D.A. with governatorial ambitions is annoyed by an investigative reporter's criticism of his criminal activities and decides to frame the reporter for manslaughter in order to silence him.
When a confused eyewitness identifies New York City cabbie Brick Tennant as a killer, he is sentenced to death for a murder that he wasn't involved in. Though no one is willing to listen to the innocent prisoner's pleas for freedom, Brick's faithful fiancée, Mary, knows that her lover is innocent because she was with him when the crime was committed. As the scheduled execution draws ever nearer, Mary begins to investigate the murder herself.
On a train headed for England a group of travelers is delayed by an avalanche. Holed up in a hotel in a fictional European country, young Iris befriends elderly Miss Froy. When the train resumes, Iris suffers a bout of unconsciousness and wakes to find the old woman has disappeared. The other passengers ominously deny Miss Froy ever existed, so Iris begins to investigate with another traveler and, as the pair sleuth, romantic sparks fly.
A chemical manufacturer is killed just after asking detective James Wong to help him. So detective Wong decides to investigate this as well as two subsequent murders.
Wealthy widow Mrs. Bramson notices that her maid is distracted, and when she learns the girl's fiancé, Danny, is the reason, she summons him in. Mrs. Bramson's niece Olivia takes a liking to Danny, and comes to believe that he may have been involved in the disappearance of a local woman.
Gabby, the waitress in an isolated Arizona diner, dreams of a bigger and better life. One day penniless intellectual Alan drifts into the joint and the two strike up a rapport. Soon enough, notorious killer Duke Mantee takes the diner's inhabitants hostage. Surrounded by miles of desert, the patrons and staff are forced to sit tight with Mantee and his gang overnight.
Dr. Janos Rukh discovers a certain type of radium that has almost magical healing properties. But the element has a dangerous side, too, and it has already started affecting Rukh. Consumed by paranoia, he begins to suspect that his wife is having an affair. Wild for revenge, Rukh hatches a deadly plot...using his own poisoned body as a weapon to kill.
Richard Hanney has a rude awakening when a glamorous female spy falls into his bed - with a knife in her back. Having a bit of trouble explaining it all to Scotland Yard, he heads for the hills of Scotland to try to clear his name by locating the spy ring known as The 39 Steps.
Holmes, retired to Sussex, is drawn into a last case when his arch enemy Moriarty arranges with an American gang to kill one John Douglas, a country gentleman with a mysterious past. Holmes' methods baffle Watson and Lestrade, but his results astonish them. In a long flashback, the victim's wife tells the story of the sinister Vermissa Valley.
While vacationing in St. Moritz, a British couple receive a clue to an imminent assassination attempt, only to learn that their daughter has been kidnapped to keep them quiet.
When legendary hunter Bob Rainsford is shipwrecked on the perilous reefs surrounding a mysterious island, he finds himself the guest of the reclusive and eccentric Count Zaroff. While he is very gracious at first, Zaroff eventually forces Rainsford and two other shipwreck survivors, brother and sister Eve and Martin Towbridge, to participate in a sadistic game of cat and mouse in which they are the prey and he is the hunter.