Gabby, the waitress in an isolated Arizona diner, dreams of a bigger and better life. One day penniless intellectual Alan drifts into the joint and the two strike up a rapport. Soon enough, notorious killer Duke Mantee takes the diner's inhabitants hostage. Surrounded by miles of desert, the patrons and staff are forced to sit tight with Mantee and his gang overnight.
Dr. Janos Rukh discovers a certain type of radium that has almost magical healing properties. But the element has a dangerous side, too, and it has already started affecting Rukh. Consumed by paranoia, he begins to suspect that his wife is having an affair. Wild for revenge, Rukh hatches a deadly plot...using his own poisoned body as a weapon to kill.
As the demand for raw silk goes sky high, crooked businessman Wallace Myton corners the market with plans to drive up the price. Determined to fulfill his contracts, manufacturer Donald Kilgore imports $3 million worth of silk to Seattle and accompanies it by special train to New York. But when his secretary is found murdered, Kilgore soon discovers Myton has planted three killers on board with orders to stop the express and its passengers dead in their tracks.
When legendary hunter Bob Rainsford is shipwrecked on the perilous reefs surrounding a mysterious island, he finds himself the guest of the reclusive and eccentric Count Zaroff. While he is very gracious at first, Zaroff eventually forces Rainsford and two other shipwreck survivors, brother and sister Eve and Martin Towbridge, to participate in a sadistic game of cat and mouse in which they are the prey and he is the hunter.
Scion of the once-rich Mitchell family, Herbert Wynn is found shot to death. Nurse Adams, bored by hospital routine, is recruited by the police to ferret out clues as she tends to Wynn's elderly aunt Julia. Jokingly given the 'rank' of Miss Pinkerton, after the famous detective agency, Adams probes into the mystery, but not before a second death.
Forced by her mean-spirited father, Lord Chief Justice James O'Brien, to marry a man she doesn't love, Connaught O'Brien gives up hope of ever with her true love, Dermot McDermot. After her father dies and a hunted rebel leader returns to town, however, Connaught finds a renewed hope that the tides of oppression will shift and she might again find happiness. This silent romantic drama, set in Ireland, is the first film in which a then-unknown John Wayne is clearly visible.