Jamie is a boorish, insensitive American twentysomething traveling in Chile, who somehow manages to create chaos at every turn. He and his friends are planning on taking a road trip north to experience a legendary shamanistic hallucinogen called the San Pedro cactus. In a fit of drunkenness at a wild party, Jamie invites an eccentric woman—a radical spirit named Crystal Fairy—to come along.
Young mattress salesman Brian decides to adopt a baby from China but is distracted when he forms a relationship with quirky, wealthy Harriet whom he meets at his mattress store. As their relationship flourishes, unbeknownst to them, a hitman is trying to kill Brian.
Befriended by aristocrat Sebastian Flyte, Oxford student Charles Ryder finds that the power and privilege experienced by the family is seductive. On a visit to the ancestral home, Brideshead, he falls in love with his friend's sister, Julia. However, as his ties to the Flytes deepen, Ryder finds himself at odds with their strong Roman Catholicism.
Holly loves Rob and tries to help him through his grief – even if it means contending with his dead girlfriend Nina, who comes back, bloody and broken, every time they make love
Arthur is a grumpy pensioner who can't understand why his wife Marion would want to embarrass herself singing silly songs with her unconventional local choir. But choir director Elizabeth sees something special in the reluctant Arthur and refuses to give up on him. As she coaxes him out of his shell, Arthur realizes that it is never too late to change.
The lives of three women have a commonality: adoption. Karen is a physical therapist who regrets that, as a teenager, she gave up her daughter for adoption. Elizabeth was an adopted child and is now a successful lawyer, but her personal life lacks warmth. Lucy and her husband have failed to conceive and now hope to adopt a baby to make their family complete.
Waitress Annie has separated from her suicidal alcoholic husband, Glenn. Glenn has become an evangelical Christian, but his erratic attempts at getting back into Annie's life have alarmed her. High school student Arthur works at Annie's restaurant, growing closer to a new kid in town, Lila, after class. When Glenn and Annie's daughter go missing, the whole town searches for her, as he increasingly spirals out of control.
Aspiring interior designer Layla is dreading the Christmastime wedding of her cousin who’s marrying Layla’s ex-fiancé. Although Seth is the one responsible for introducing the bride and groom, she begrudgingly accepts his offer to be her date as she’s out of options. Seth gets carried away at the reception and announces they’re engaged, forcing a mortified Layla to keep up the pretense.
Cuba is not a country for young gays. Teen rent boy Reinier falls in love with a mate in the slum soccer field in their neighbourhood in Havana. Although obsessed with moneymaking to hold up his baby, teen wife, and wife's grandma, gambler Reinier always fails to get the stroke of luck he looks for. At the same time he cannot help being infatuated by Yosvani. Handsome Yosvani will give up his older, wealthy girlfriend (whom he hooked up to pay for a lavish life in the big city), and the work he does for her father, a loan thug, so much in love he is with Reinier. But the boys would fight hard to keep this love in the reckless Havana streets.
Henry Moon is captured for a capital offense by a posse when his horse quits while trying to escape to Mexico. He finds that there is a post-Civil War law in the small town that any single or widowed woman can save him from the gallows by marrying him.
During the revolution, a high-stakes gambler arrives in Cuba seeking to win big in poker games. Along the way, he meets and falls in love with the wife of a Communist revolutionary.
Halley is convinced true love doesn't exist based on the crazy relationships around her. Her mother is divorcing her father who is dating a younger woman Halley can't stand. Her crazed sister is planning a wedding but has second thoughts and her best friend has fallen madly in love for the first time leaving Halley to feel even more alone.
Mickey Gordon is a basketball referee who travels to France to bury his father. Ellen Andrews is an American living in Paris who works for the airline he flies on. They meet and fall in love, but their relationship goes through many difficult patches.
Tilo is an Indian shopkeeper in America with an ability to see the future and a magical connection to powerful spices, which she uses to help her customers satisfy their various needs and desires. One day she falls in love with an American man. But the spices forbid it.
The vaudeville act of Harriet and Queenie Mahoney comes to Broadway, where their friend Eddie Kerns needs them for his number in one of Francis Zanfield's shows. When Eddie meets Queenie, he soon falls in love with her—but she is already being courted by Jock Warriner, a member of New York high society. Queenie eventually recognizes that, to Jock, she is nothing more than a toy, and that Eddie is in love with her.
A fugitive stumbles onto a movie set just when they need a new stunt man, takes the job as a way to hide out and falls for the leading lady while facing off with his manipulative director.