Florida, 1830 - Of all eastern Native American tribes, only the Seminoles have resisted being moved to reservations. Having retreated to Florida, they live a simple horticultural life. But white plantation owners, angry at the increasing numbers of black slaves fleeing to Seminole protection, want to take their land. Plantation owner Raynes, in particular, has convinced the military to wipe out the Seminoles. His rival Moore, a sawmill owner from the North who has a Seminole wife, is against slavery and considers it unprofitable. Chief Osceola sees the coming danger; he tries to avoid provoking the whites, but cannot prevent the war that breaks out in 1835.
George Benton returns from school to his brother Jonathan's farm as a doctor and marries his fiancé Lory, but happiness doesn't last long. The Fargas brothers provide a bloodbath at the ranch and are able to divert suspicion from themselves onto a gang of passing outlaws, but one of the family has survived the massacre and knows who the actual killers are.
Ross Bodine and Frank Post are cowhands on Walt Buckman's R-Bar-R ranch. Bodine is older and broods a bit about how he will get along when he's too old to cowboy. Post is young and rambunctious and ambitious for a better life than wrangling cows. When one of their fellow cowboys is killed in a corral accident, Post suggests a way into a better life for himself and his friend: robbing a bank. Bodine reluctantly joins in the plan and the two contrive to rob the local bank. They make good their escape initially, but Walt Buckman and his two sons, John and Paul, are incensed at this betrayal by their own trusted employees. John and Paul set out to bring Bodine and Post to justice.
"Whity" is the mulatto butler of the dysfunctional Nicholson family in the American Southwest in 1878. The father, Ben Nicholson, has an attractive young wife, Katherine, and two sons by a previous marriage: the homosexual Frank and the feeble-minded Davy. Whity tries to carry out all their orders, however demeaning, until various family members ask him to kill some of the others.
Arms trafficking with the Indians on the one hand and acquiring documents concerning the ownership of a goldmine on the other are the principal interests of Quin and Gomez, the highly suspicious guests at Papa Martinez' inn. The unexpected arrival of the sheriff Thomas, and the journalist, George, upsets the plans of the two unsavoury allies and they have to try every kind of trick to win out against such adversaries.
A con artist arrives in a mining town controlled by two competing companies. Both companies think he's a famous gunfighter and try to hire him to drive the other out of town.
The Benson brothers, who are smuggling guns across the Mexican border, kill King's brother and rape his wife. King must stop their illegal activities, find who is behind them and gain revenge for his family.
The Mormon pastor Mateo is obsessed by the murder of his father, which he witnessed as a child, but raises a church and preaches against violence. The gunman Gumaro helps the preacher when two outlaws show up and kills one of them. Four brothers of the dead outlaw attack the preacher's ranch and kill his pregnant wife, his son, a worker and leave the pastor for dead. He recovers, forgets his sermons and sets out to take vengeance on the murderers.
The Cortez brothers rob a bank and flee beyond the Mexican border. On their trail are various people, each for a different reason: Sheriff Fulton is sent by the robbed bank to recuperate the money; Django, a head-hunter, is after them for the reward money; Pickwick is after a saddle stolen from him by the Cortez brothers; Pedro and Dolores, saloon owners, also would like to have the loot.
Dale and Helen Brais are a marriage of farmers who subsist on what little they manage to get from their land. One stormy night, a stranger enters their home to rob and Dale kills him incidentally. The intruder is Red Burket, head of a band that is dedicated to sabotage the new railway line and there is a bounty on his head of $20,000. What seems the solution to the problems of the couple becomes the beginning of a nightmare.
A vengeful widow hires a professional killer to train her son so that he can hunt down and kill the men who murdered her husband. The quest for revenge soon becomes an obsession.
Macho Callaghan is a lieutenant in the Federal Guards and his job is to capture Butch Cassidy, Ironhead, and their band of outlaws. Getting in touch with Ironhead, Macho finds a way of being hired by the outlaws. But when the two leaders quarrel and decide to separate, Macho manages to convince Ironhead to attack Butch Cassidy.