Buck Minor was the most detested man in Wolf Hollow, partly because he was quarrelsome and treacherous, partly because he abused and neglected his little wife, Molly, whom all the camp adored, and for whose sake it tolerated Buck.
A sheriff saves a Mexican from being hanged for horse theft. In a gesture of thanks, the Mexican writes the word "gratitude" upon a card. After rending the card in two, he gives one half to the sheriff. Many years later the sheriff, still carrying his half of the "gratitude" card, becomes the captive of desperados. One of these greasy varmints grabs a tobacco pouch from the bound sheriff's pocket, noticing the timeworn card...
Among the tall trees and mountains of the Far West, a father, son and daughter dwell peacefully in their mountain cabin, close to nature, seldom hearing of the great restless world outside, happy in their isolation. Jack, the son, visiting town on business, is tempted into a gambling saloon and takes part in a game of cards. Dalton, a gambler, undertakes to fleece the boy. The result is a fight in which Dalton is shot, and Jack becomes a fugitive.
Road Agents begins as a pair of outlaws prepares to rob a stagecoach. Donning masks and brandishing six-guns, the bad guys relieve the passengers of their valuables and also make off with a box full of payroll money. As the sheriff organizes a posse, the bandits are seen dividing their loot. The greedier of the two crooks beats up his partner and absconds with their ill-gotten gains. The other bandit, thirsting for revenge, joins the sheriff's posse to track down his former chum.
A gang of outlaws are planning a bank robbery. After making preparations, they commit the robbery and make their escape amidst a sharp exchange of bullets. They return to their meeting place, and then hurriedly continue onwards, with lawmen close behind them.
A sheriff apprehends a bank robber and recovers the money. On the way back to town, the sheriff loses the recovered money in a crooked card game. The bank robber helps him recover it.
In a saloon in a Mexican border town, a group of cowboys, including a Mexican named Pedro, play poker. One man is discovered cheating, and is shot dead by Pedro, who is wounded as he attempts to escape. Pedro is followed home by the local sheriff, who proves the next victim of Pedro's quick temper and pistol. Pedro's wife, Juanita, is thrown into jail, but he manages to break her out. They head for the border, unaware that a posse is waiting for them.
As a result of a stagecoach hold-up and other crimes, Buck Brady has become known locally as the "King of Bandits". The sheriff posts a $1000 reward for Brady, dead or alive. Soon a full-scale effort is underway to capture the bandit king.
As a young couple are courting, they are rudely interrupted and split up. The man is seized and is turned over to a gang of toughs who want to hang him. Though she is greatly outnumbered, the young woman wastes no time in making a determined effort to rescue him.
At dawn, two cowboys set out to scout ahead; as soon as they are on the trail of a herd of wild horses, they attempt to surround them and drive them back. A rapid stamping alerts their companions, who prepare the lassos; the ropes whistle, wind around the necks of the panicked beasts, which take a few more steps then, strangled and panting, are brought back captive. In the evening, they camp. Large fires are lit around which men and beasts settle down to sleep, not without a good guard being kept in the surrounding area. Meanwhile, the Apaches creep under cover of night to the American camp and succeed in seizing the captured beasts. Following this abduction, a frantic pursuit begins across the vast solitude of the Far West.