The tranquility of a small town is marred only by sheriff Tod Shaw's unsuccessful courtship of widow Ellen Benson, a pacifist who can't abide guns and those who use them. But violence descends on Ellen's household willy-nilly when the U.S. President passes through town... and slightly psycho hired assassin John Baron finds the Benson home ideal for an ambush.
Don Gregor, the son of famous plastic surgeon Dr. Boris Gregor, begins to hang around with young criminal Vic Brady and carry a gun. The pair attempt an armed holdup, and when things start to go wrong Gregor accidentally kills a night watchman. Fearing that Gregor plans to turn himself in, Brady kills him and blackmails Dr. Gregor into giving him a new face.
London, 1888: on the night of the third Jack the Ripper killing, soft-spoken Mr. Slade, a research pathologist, takes lodgings with the Harleys, including a gloomy attic room for "experiments." Mrs. Harley finds Slade odd and increasingly suspects the worst; her niece Lily (star of a decidedly Parisian stage revue) finds him interesting and increasingly attractive. Is Lily in danger, or are her mother's suspicions merely a red herring?
On a tramp steamer off Central America are Mr. and Mrs. Sheppard, five prisoners en route to a Nicaraguan prison, and Corbett, an American carrying money for a Honduran counter-revolution. Denied permission to land in Honduras, Corbett releases the prisoners and with their aid hijacks the ship. They land, taking the wealthy Sheppards as hostages, and start the arduous trip upriver to Corbett's rendezvous, meeting jungle hazards
Whitney Cameron is in a quandary: he's attracted to his beautiful sister-in-law, Lynn, but also harbors serious suspicions about her. Her husband, Cameron's brother, died under mysterious circumstances, and now that the death of her stepchild, Polly, has been attributed to poisoning, he suspects that Lynn is after his late brother's estate, and killing everyone in her way.
In New York City, an insolent pickpocket, Skip McCoy, inadvertently sets off a chain of events when he targets ex-prostitute Candy and steals her wallet. Unaware that she has been making deliveries of highly classified information to the communists, Candy, who has been trailed by FBI agents for months in hopes of nabbing the spy ringleader, is sent by her ex-boyfriend, Joey, to find Skip and retrieve the valuable microfilm he now holds.
Roy and Gilbert's fishing trip takes a terrifying turn when the hitchhiker they pick up turns out to be a sociopath on the run from the law. He's killed before, and he lets the two know that as soon as they're no longer useful, he'll kill again. The two friends plot an escape, but the hitchhiker's peculiar physical affliction, an eye that never closes even when he sleeps, makes it impossible for them to tell when they can make a break for it.
Rose Loomis and her older, gloomier husband, George, are vacationing at a cabin in Niagara Falls, N.Y. The couple befriend Polly and Ray Cutler, who are honeymooning in the area. Polly begins to suspect that something is amiss between Rose and George, and her suspicions grow when she sees Rose in the arms of another man. While Ray initially thinks Polly is overreacting, things between George and Rose soon take a shockingly dark turn.
A Dutch company's owner bankrupts his own company, burns the incriminating ledgers and plans to run to Paris with the company funds but he is caught in the act by his accountant who challenges his actions, leading to a reversal of roles.
A plastic surgeon changes the face of a female convict to match that of the beautiful woman who broke his heart and left him. He marries the convict but trouble starts when his true love returns.
Mystery novelist Janet Frobisher, lives in an isolated house, having been separated for years from her criminal husband. She has fallen in love with her secretary's fiancé and when her estranged husband unexpectedly returns, Janet poisons him, but just as she's about to dispose of the body, one of her husband's criminal cohorts also shows up.
Vincent Lubeck is a vicious ex-convict. His criminal activities are despised by his family, but he uses and abuses them in the course of his crimes. Eventually his own brother must stand up to him.