Sherlock Holmes investigates when young women around London turn up murdered, each with a finger severed. Scotland Yard suspects a madman, but Holmes believes the killings to be part of a diabolical plot.
The famous Borgia Pearl, a valuable gem with a history of bringing murder and misfortune to its owner since the days of the Borgias, is brought to London, thanks in part to Sherlock Holmes. But before long the jewel is stolen, due to an error on Holmes' part, and shortly thereafter, a series of horrible murders begin, the murderer leaving his victims with their spines snapped and surrounded by a mass of smashed china.
When a woman is found dead with her throat torn out, the local villagers blame a supernatural monster. But Sherlock Holmes, who gets drawn into the case from nearby Quebec, suspects a human murderer.
When a treasure hunter seeks a downed airplane in the jungles of Africa, he encounters one of the passenger's young daughter, now fully grown, and with a gorilla protector.
Sherlock Holmes investigates a series of so-called "pajama suicides". He knows the female villain behind them is as cunning as Moriarty and as venomous as a spider. Based on "The Sign of Four" and the short stories "The Dying Detective", "The Final Problem", "The Speckled Band" and "The Adventure of the Devil's Foot".
During WWII several murders occur at a convalescent home where Dr. Watson has volunteered his services. He summons Holmes for help and the master detective proceeds to solve the crime from a long list of suspects including the owners of the home, the staff and the patients recovering there.
One dark and stormy night, an escaped convict, an embezzler, a runaway daughter, her intended and her father, and a gangster take refuge in a remote inn called "The Black Raven" after the nickname of a second gangster who owns it; and murder ensues.
After one member of their group is murdered, the performers at a burlesque house must work together to find out who the killer is before they strike again.
In World War II, a British secret agent carrying a vitally important document is kidnapped en route to Washington. The British government calls on Sherlock Holmes to recover it.
A young woman's husband has been imprisoned for a crime he didn't commit. In order to be near him to try to help him get his sentence overturned, she moves into a boardinghouse near the prison whose residents are the wives of inmates.
In the midst of World War II, Sherlock Holmes rescues the Swiss inventor of a new bomb-sight from the Gestapo and brings him to England, where he quickly falls into the clutches of the evil Professor Moriarty.
A seemingly charitable soup kitchen operator (who moonlights as a criminology professor) uses his Bowery mission as a front for his criminal gang. Police attempt to close in on the gang as they commit a series of robberies, murders and bizarre experiments on corpses.