As a penalty for fighting fellow classmates days before graduating from West Point, J.E.B. Stuart, George Armstrong Custer and four friends are assigned to the 2nd Cavalry, stationed at Fort Leavenworth. While there they aid in the capture and execution of the abolitionist, John Brown following the Battle of Harper's Ferry.
Wanted by the law in New York, Dr. Steve Kells heads west and arrives in an area controlled by an outlaw gang known as the Border Legion. When the gang's boss is wounded, they kidnap Kells and force him to remove the bullet. Not allowed to leave and being a wanted man, he joins the gang. Now wanted as a gang member also, he nevertheless plans a raid that will lead the entire gang into a trap.
Marshal Tim Donovan has been sent to investigate a series of holdups. Posing as a card sharp he soon believes he knows who is tipping off the outlaws. So he sets up a fake shipment knowing that if the stage is robbed the contact person will be identiifed. But the day the stage is due the Sheriff arrests the gang Tim was expecting to do the robbery.
Storm is out to wreck Ace's stage line. When Tex arrives to help Ace, Storm brings in hired killer Mule Bates. But Tex and Bates know each other and the two devise a plan to fool Storm.
Bill Hickok, assisted by Calamity Jane, is after a foreign agent and his guerrilla band who are trying to take over some western territory just as the Civil War is coming to a close.
When Moreland's henchman attack Bob Horner the Range Busters break it up. Horner dies but they get the baby Moreland was after. He must have it to become it's guardian and take control of the Horner ranch. When the henchmen catch up with Alibi, they take the baby cradle not realizing Alibi has substituted his dummy Elmer. Crash having evidence Moreland is the one they want, now has a plan to expose him.
In his first starring Western for RKO, young Tim Holt must not only carry on his father's freight business but also hunt down his murderer. A certain Matt Gardner wants to corner the freight business to Pecos and persuades young Zack Sibley's wagon master to switch sides. Zack also earns the enmity of Gardner's son Coe, who takes umbrage to the youngster's flirtation with pretty Helen Lee. It all comes to a head during a food shortage in Pecos, a near-disaster that persuades the wagon master to switch sides once again. When the dust settles, Zack learns that old man Gardner is actually Carl Anderson, the man who murdered his father.
In the second of the "Billy the Kid" series from PRC that starred Bob Steele, Billy the Kid is being held on a trumped-up murder charge in a Mexico jail. He escapes and meets his pal, Fuzzy Jones, in Corral City, Texas, which is taking a holiday to allow the cowpunchers of the Lazy A Ranch their periodic spree. In the saloon, Billy is recognized by Dave Hendricks and Flash, two the Lazy A's bed men, as the rider who had held them up after they had robbed the express wagon a few hours earlier. Outside, Billy is ambushed and slightly wounded, and is taken to the express office by Jim Morgan where Mary Barton, the local agent, agrees to tend him until the doctor arrives. Billy turns over the loot he took from the outlaws and he is appointed sheriff, with Fuzzy as his deputy. The Lazy A gang brings in a noted gunfighter, Gil Cooper, who turns out to be Billy's brother. Billy, Gil and Fuzzy eventually rout the outlaw gang, and Gil remains behind with Mary as Billy and Fuzzy ride off.
Trouble in Colorado is tying up Union troops needed back east during the Civil War and Lieut. Burke is sent to investigate. Macklin and his gang are causing the problems and Capt. Mason joins them. When Burke catches up with them he also finds Mason, his brother.
The drought-plagued ranchers of Sundown have to market their cattle at a loss in order to meet mortgage payments held by banker Cylus Cuttler. Then, Sheriff Tex Rockett is forced to quarantine all the cattle on the local ranches because of a hoof-and-mouth disease outbreak. Steve Davis herds his cattle to the railhead anyway, and Tex is forced to arrest him. Urged on by the banker's son, Nick Cuttler, the angry ranchers storm the jail, but Steve's sister Bee persuades them to await the trial. Steve, with Nick's help, breaks jail and is told he must kill Tex to aid the ranchers. Meanwhile, government man Bret Stockton and Tex see Nick and his men treating cattle in an unusual way. Tex finally proves that the Cuttlers have been treating the cattle with acid to give a false impression of the hoof-and-mouth disease.
A phantom-like gunman is murdering the hands at the Circle T Ranch and the Range Busters are recruited by its owner to stop the "phantom". Only, the ranch owner is killed before they can arrive. First film in the Range Buster series.
While Sam Houston in in the nation's capital trying to get Texas into the Union, his aide is trying to impose a self-serving tax on the use of the Santa Fe trail. The lady owner of a wagon train is using the trail, and a Texas Ranger comes to her assistance.
Sgt. Renfrew and Constable Kelly go aloft to search for a plane missing with a shipment of gold from the Yukon Mine Company. Inventor Speavy has devised a power ray which disrupts electrical impulses, and Morgan and his gang of crooks has brought in Prof. Lewis to increase the ray's range, telling him he's helping the government develop this new weapon. Speavy spills the beans to Prof. Lewis and his daughter Madeleine,and Morgan threatens to implicate them in his crimes unless they cooperate. Morgan kills Speavy when he tries to warn Renfrew, but when Madeleine stows away on board the doomed plane Renfrew is piloting, will the crooks be able to make Prof. Lewis use the power ray to bring the plane down?
The Carson City Kid and partner Laramie are outlaws. When his partner is caught the Kid, his identity being unknown, takes a job in Jessup's saloon. Here he see Jessup cheat Waren out of his money. Warren then robs Jessup posing as the Kid but gets caught. To gain his freedom, Laramie identifies Warren as the Kid. Realizing Jessup is the man that killed his brother, the Kid must find a way to clear Warren and get Jessup.