One day in the heart of Seoul, a dead body is found in a man's suitcase. A former forensic pathologist for the National Forensic Service becomes the prime murder suspect. However, the case is baffling and a profiler is brought in to help the investigation by figuring out why a forensic pathologist would choose to become a criminal.
Killian Curse tells 21 stories, of 21 kids, from room 21, who must each face a demon sent from the demon world by the evil Charles Killian, who founded their school in 1906.
To break the curse, room 21 must defeat over half of these demons or Killian will return from the dead and seek vengeance for his tragic death one hundred years ago.