Cousins Jim and Ned Thorpe are best friends, but that comes to an end when they both vie for the affections of Eve Marsham, and Ned wins her. Jim leaves for South America, but when he returns some time later he finds that things have drastically changed--Ned is now a hardened criminal and, in addition, is badly mistreating his wife Eve.
In 1853, young Southerner Don Buckner goes west in search of gold to recoup his dwindling fortune, spent mostly on his new bride, Elizabeth. During the years of his absence he fails to communicate with his wife or his mother Margarite, even when he strikes gold, because he hopes to make this good fortune a surprise.
The unscrupulous attempts by speculators Dr. West and Jim Prince to have a railroad pass through lower California are met with opposition by Spanish landowners led by Dona Maria Saltonstall, who tries flirting with West to restore their property. Pereo, a religious fanatic who works for Dona Maria, believes in the curse of the Gray Wolf's Ghost: if a member of Dona Maria's family mates with an alien, fortune and life will be lost. Meanwhile, West's son Harry, whom he deserted years before, comes to avenge the wrong done to his mother.
Following a brutal attack in which her husband and children are murdered, and she is left for dead, Rebecca Falcon rises from the carnage of her former life hellbent on revenge as a bloodthirsty vigilante called Mia.
Ann Lytton arrives in a small Arizona town just as ranchman Bruce Baynard brings a man into the hotel who is unconscious from drink. The man proves to be Ann's husband Ned, whom Bruce takes to his ranch in order to reform. When Ann comes to visit, Ned accuses her of having an affair with Bruce and, to punish her, he forces her to go to the mine which he has swindled from Benny Lynch's father. Fearing Lynch's vengeance, Bruce has warned Ann not to allow Ned near the mine, and so Ann sends Bruce an "SOS" via his horse Abe. Bruce manages to save Ned, but Lynch finally exacts his revenge by killing him, thus freeing Ann to marry Bruce.
After his assistant, Bud Lester, is killed, Texas Ranger Speedy Meade bids farewell to his girl friend, convent student Mary Dillman, and sets out to break up a gang of cattle thieves operating on the border.
A feud over boundaries between the McKinstry and Harrison families, both from Kentucky, but squatting in California in search of gold, has caused Cressy McKinstry to show disdain for Joe Masters, a cousin of the Harrisons, even though she secretly loves him.
The Earl of Dunhaven, who disinherited his son for marrying an American, tries, on his deathbed, to leave his estate to his nephew, the Honorable Guy Wyndham. To stop him, the Dunhaven solicitor, John Grahame, travels to America and finds the earl's grandson, Jim Dunn, a Wyoming cowpuncher.
Jerry Jerome, a rich young Wall Street broker, follows doctor's orders and goes West to relieve strain. He stops at the ranch of Jim Yancy, then agrees to be the maid of the farmhouse to earn his keep, because he is attracted to Yancy's daughter Ruth. After a series of stagecoach robberies by a masked man wearing a blue bandanna, Jerry, the new man in town, is suspected.
In the ashes of the Civil War, two battered gunslingers-one Union, one Confederate, chase a gang into a ghost town with a blood-soaked past. But it ain't just outlaws lurking in Purgatory. Something ancient. Something evil. And it wants revenge. Saddle up, sinner-this ride is going straight to hell.
Norman Draper, a Texas Ranger sent to round up a band of cattle rustlers, finds Phillip Carlson at the deathbed of his wife and assists him in burying her. Meanwhile, cow thieves are plaguing Marcos Valverde and his daughter Elicia; and Leon Serrano, the local deputy sheriff (actually the leader of the rustlers), realizing the community will demand a victim, arrests Carlson, who has innocently bought a stolen horse from the thieves. Draper rescues him from a lynching party and learns the whereabouts of the rustlers. Leon Serrano is unmasked as the culprit and then is arrested by Draper, who gives his reward to Carlson and is himself rewarded by the love of Elicia.
When the other members of a stranded theatrical company pool their funds to return to San Francisco, Yvonne Laraby remains in Colt City, Nevada, at the request of Andrew Reed, an oil company foreman, to consider his marriage proposal. There she meets oil well owner Clay Truxall, a former acquaintance, who asks her to become his secretary. Yvonne falls in love with Truxall and persuades Reed to return to his sweetheart, Marie Curtis, whom he had deserted for Yvonne.
Small town sheriff "Silent" Davidson tries to protect aging sheep rancher Scott Martin and his daughter, Jean, from the predations of local cattlemen. Head cattleman Pete Kane and banker Jeff Sedley ambush the old man and frame the sheriff for his murder, but Scott is only badly wounded. Recovering consciousness, he tells Jean who the real culprits are. However, Kane seizes and imprisons her. Ultimately, Silent breaks out of jail, finds and frees Jean from her bonds, proves his innocence, and brings Kane and Sedley to justice. Naturally, he wins Jean's heart.
Dave Sethman has been brought up to believe that he is the half-breed son of Sethman, a tough rancher who opposes the plans of John Crawford, an eastern industrialist, to buy up a group of ranches. Crawford comes west with his daughter, Jean, and attempts to break the elder Sethman's opposition. Dave saves Jean from a runaway horse and later protects her when Murdock, Crawford's unprincipled assistant, makes unwanted advances. Sethman plans to rustle Crawford's cattle and is mortally wounded by him, telling Dave, as he lies dying, that Crawford is Dave's real father from whom he was stolen as an infant. Dave and Crawford are reconciled, and Crawford, whom Dave has shot in the hand, tells the boy that Jean is his adopted daughter, leaving the way free for a romance between the young people.