Central America in 1915. It is the age of revolutions, tyranny, captains and colonels in a small provincial town that is often invaded by some revolutionary group or other. There is a brothel of which the Madame Simone and most of the girls, are French. Many of the girls are in love with rebel leader Carlos Ribas and when government troops re-occupy the area, they hide him. When the soldiers discover him, they take both him and the girls prisoner. The governor sends the girls out in a cart to amuse the troops, but they manage to escape along the way and take refuge in a convent where they take over the nuns.
Willie Duggans, a tenderfoot from the east, arrives in the wild west and soon experiences its violence. Willie discovers the easy money in bounty killing and must choose between that violent lifestyle and the love of a beautiful saloon singer.
Jory is a fifteen-year-old boy who joins a horse-drive after his father is killed by a drunkard. The drive's leader and a likable cowhand take the boy under their wing, and find that tragedy has taught him how to take care of himself better than anyone could expect.
Frenchie Fontaine sells her successful business in New Orleans to come West. Her reason? Find the men who killed her father, Frank Dawson. But she only knows one of the two who did and she's determined to find out the other.
Jim Wyngate, an English aristocrat, comes to the American West under a cloud of suspicion for embezzlement actually committed by his cousin Lord Henry. In Wyoming, Wyngate runs afoul of cattle rustler Cash Hawkins by rescuing the Indian girl Naturich from Hawkins. Wyngate marries Naturich, but then learns that his cousin Lord Henry has been killed and has cleared his name before dying. As Wyngate has long loved Lady Diana, Lord Henry's wife, he is perplexed at his situation. But fate takes a hand and resolves matters as Wyngate could not have predicted.
A wagon train heading west across the great desert runs out of water, and is attacked by Indians. One man -- their last hope -- is sent out to find water.
A group of young thugs rides into the town of Dawson and take it over. When the cowardly sheriff is unable to restore control, the parents of the leader must take action. The leader's father is an infamous ex-gunfighter, and he straps his guns on one more time.
Though he fought for the North in the Civil War, John is asked by the Governor of Texas to get rid of some troublesome carpetbaggers. He enlists the help of Holden before learning that Holden too is plundering the local folk.
Mark Fallon, with partner Kansas John Polly, tries to introduce honest gambling on the riverboats. His first success makes enemies of the crooked gamblers and of fair Angelique Dureau, whose necklace he won. Later in New Orleans, Mark befriends Angelique's father, but she still affects to despise him as his gambling career brings him wealth. Duelling, tragedy, and romantic complications follow.
At the turn of the century Rose and ex-showbiz friend Molly get involved in selling steel. When they come unstuck with corsets they embark on the even more hazardous project of selling barbed wire to highly suspicious Texas cowboys.
Upon the death of his father, who was the tribal chieftain, Joe Thunder Horse returns to the reservation of his youth, only to discover that his people are dying of various diseases and are being systematically cheated of their possessions and basic rights by crooked Indian agents. He heads to Washington in hopes of righting these wrongs, only to experience prejudice and hatred all along the way.
In Medicine Bend, a crooked businessman has the town mayor and sheriff in his pocket while his henchmen raid the wagon trains passing through the region.