Heading through Colorado Territory in search of gold and women, Alferd Packer and his group of bemused companions find themselves lost, starving and musically inspired by the obstacles they confront along the way, including a die-hard Confederate cyclops, a trio of surly trappers, a tribe of Japanese-speaking "Indians," and ultimately, each other.
A scruffy garbage boy becomes the pupil of famed gunfighter Talby, and the stage for confrontation is set when the gunman overruns the boy's town through violence and corruption.
By his dying father's last wish Joe is sent to the Wild West to become a real guy. The dreamy young man despises guns and fights likes poems and prefers bicycles to horses. Now his three teachers footpads all of them shall teach him otherwise. This doesn't work until Joe has to defend himself against gunman Morton who's jealous of Joe's love to rancher Ohlsen's beautiful daughter.
El Chuncho's bandits rob arms from a train, intending to sell the weapons to Elias' revolutionaries. They are helped by one of the passengers, Bill Tate, and allow him to join them, unware of his true intentions.
Two miners agree to guide a mysterious woman, who has appeared in their camp from nowhere, to a nearby town; but soon, because of her erratic behavior, they begin to suspect that her true purpose is quite different.
Detective Matthias Breecher, hired to track down the worst of the Confederate war criminals, roams the Old West seeking justice. His resolve is tested when he meets a determined pioneer woman who is far more than she seems.
Forester, a ruthless oil baron, wants to create a war between the native American tribes and the white men. Old Shatterhand, Winnetou and their sidekick Castlepool try to prevent this.
Drifter Cole Harden is accused of stealing a horse and faces hanging by self-appointed Judge Roy Bean, but Harden manages to talk his way out of it by claiming to be a friend of stage star Lillie Langtry, with whom the judge is obsessed, even though he has never met her. Tensions rise when Harden comes to the defense of a group of struggling homesteaders who Judge Bean is trying to drive away.
Rollins' gang wants to grab land by inciting the settlers in a war against the Indians but Winnetou and Old Shatterhand try to keep the peace, until Rollins frames Winnetou up for the murder of Jicarilla Chief's son.
Several pillars of society have robbed an Army safe containing $100,000 so they can buy the land upon which the coming railroad will be built. But they haven't reckoned on the presence of the master gunslinger, Sabata.
Forced to trade his valuable furs for a well-educated escaped slave, a rugged trapper vows to recover the pelts from the Indians and later the renegades that killed them.
Arms dealer Yolaf Peterson aims to make a sale to guerilla Mongo, but the money is locked in a bank safe, the combination known only to Professor Xantos, a prisoner of the Americans. Yolaf agrees to free Xantos, accompanied by reluctant guerilla Basco, but a former business partner of Yolaf's- John 'The Wooden Hand', has other ideas.
Blaise Starrett is a rancher at odds with homesteaders when outlaws hold up the small town. The outlaws are held in check only by their notorious leader, but he is diagnosed with a fatal wound and the town is a powder keg waiting to blow.
A prospector sells his wife and daughter to another gold miner for the rights to a gold mine. Twenty years later, the prospector is a wealthy man who owns much of the old west town named Kingdom Come. But changes are brewing and his past is coming back to haunt him. A surveyor and his crew scouts the town as a location for a new railroad line and a young woman suddenly appears in the town and is evidently the man's daughter.
Newly appointed sheriff Pat Garrett is pleased when his old friend Doc Holliday arrives in Lincoln, New Mexico on the stage. Doc is trailing his stolen horse, and it is discovered in the possession of Billy the Kid. In a surprising turnaround, Billy and Doc become friends. This causes the friendship between Doc and Pat to cool. The odd relationship between Doc and Billy grows stranger when Doc hides Billy at his girl Rio's place after Billy is shot.
Buffalo Bill plans to put on his own Wild West sideshow, and Chief Sitting Bull has agreed to appear in it. However, Sitting Bull has his own hidden agenda, involving the President and General Custer.
A gang of cold-blooded outlaws narrowly escapes a blood-soaked bank robbery in a grimy frontier town. With a notorious bounty hunter hot on their trail, these nefarious criminals desperately need a place to hide out before night falls. Fate brings them to the home of the Tildons, a seemingly innocent family with two feisty daughters. As the men settle in, an impetuous game of cat and mouse plays out during the cold, black night. Come morning, nothing will ever be the same.