After blaming Britt for his wife's decision to stay with the Native Americans who captured her, an abusive husband organizes a party of vigilantes to accompany him into Indian territory.
Buck Roberts is leading a wagon train of railroad supplies and Jim Corkle and his henchman Loder are out to stop them by using white men dressed as Indians for the attacks.
Zara Montalve, half Spanish and half America, returns to her native California in time to see her parents murdered for their hacienda and gold by Sheriff Jim Harding and his gang. Posing as Lola Belmont, an American visiting from Detroit, teams up with Joaquin Murietta, posing as Carlos Del Rio, to form a Robin-Hood type band that takes vengeance on the gang and restores stolen gold to its rightful owners, aided by militia leader Dan Hinsdale.
Billy Wade is an ex-gunslinger who is approached by his outlaw brother Matt, not long out of prison, to help him with a big-time robbery. Matt forces Billy's participation with an offer he cannot refuse, unaware that Billy is actually working on the side of the law.
A vengeful widow hires a professional killer to train her son so that he can hunt down and kill the men who murdered her husband. The quest for revenge soon becomes an obsession.
Roy Rogers rides to the rescue when a bank robber's orphaned son (Tommy Cook), who is living at a ranch for homeless boys run by Gabby Whittaker (George "Gabby" Hayes), attracts the attention his father's rowdy gang, who want to claim the boy's inheritance for themselves
Al arrives in town which is ruled by Lash who has taken possession of one gold mine and is now aiming to get the other which is owned by old Johnny. Al is the only one to support Johnny but still the old man is ambushed and killed.
After the war of secession, the aging Cordeen, who owns thousands of acres in Texas, rules his numerous and quarrelsome sons with an iron hand. He sends them out to deal with the threat of the representatives from the North. However, not all the sons share their father's unlimited hatred for the Northerners and they find it increasingly difficult to obey his despotic commands. To add to the family's unrest, a prodigal son decides to return to the fold, provoking two other sons to down tools and leave. Cordeen, outraged, pursues them and tries to kill them. An absurd family feud ensues, prolonged by the participation of the entire Cordeen family.
The Cortez brothers rob a bank and flee beyond the Mexican border. On their trail are various people, each for a different reason: Sheriff Fulton is sent by the robbed bank to recuperate the money; Django, a head-hunter, is after them for the reward money; Pickwick is after a saddle stolen from him by the Cortez brothers; Pedro and Dolores, saloon owners, also would like to have the loot.
Wells Fargo hires bounty hunters to protect its gold transports from the notorious outlaw Glenn Kovacs. Jeff Sullivan, one of the hired gunmen, buys the freedom of Dan Barker, a prisoner who may lead him to Kovacs. When Barker escapes from Sullivan, the other bounty hunters pursue him also, leading to the ultimate showdown between all parties.
Kirk Baxter has been sent to investigate murder and robbery involving gold shipments. Identifying a gang member by his bullets, he uses that man's horse to locate and join the gang. He learns the gang is tipped off to the shipments by a mine employee using carrier pigeons. But the next message reveals his true identity and he is made a prisoner.
Saunders with his Cattlemen's Protective Agency is running roughshod over the ranchers. Lawyer Larry Kimball is fighting him but he needs a rancher that will stand up with him against Saunders. He finds him when Lou Gehrig retires from baseball to take up ranching. Lou expects to relax on his ranch but quickly joins Larry in the fight.
Captain Hunt of the cavalry is trying to promote good relations with the Indian chief Acoma. But Hunt's superiors in the military insist on pursuing policies that will provoke a conflict, and Chief Acoma is not willing to let himself be insulted.
Roy Rogers, Smiley Burnette and the Sons of the Pioneers go undercover to help Texas Governor Russell Hicks stop World War II Axis sympathizers from blowing up U.S. warehouses.