After Bob Lansing (Jay Wilsey as Buffalo Bill Jr). is involved in a nightclub scrape, where he meets Montana rancher Madge Holt (Allene Ray)), his father sends him out west with his chauffeur Ben (Ben Corbett). In Montana, they are mistaken for rustlers Dick (Tom London) and Jim (Yakima Canutt), and Bob again meets Madge, who recognizes him but wishes to make things difficult for him.
Bill travels to a new state after the outlaw Scarface saves him from a lynch mob. There he takes a job on the Barton ranch and joins in the fight against gang leader Larkin. Finding a wounded Scarface he helps him recover. Arrested by Larkin's stooge Sheriff, and with another lynch mob after him, he once again needs Scarface's help.
The parents (Horace B. Carpenter)(Vane Calvert) of Smokey Smith (Bob Steele) are murdered while traveling with a wagon train that is attacked by outlaws. Smokey swears revenge but his only possible chance lies in finding the member of the border-gang who took a ring from his father's finger. The sheriff (Earl Dwire) of a nearby border town makes Smokey a deputy after the latter saves his life when outlaws attack a stagecoach the sheriff is escorting. This enables Smokey to find the hideout of the gang that killed his parents, and he, posing as a wanted man, is able to join the gang. He soon incurs the wrath of gang-member Kent(Warner Richmond), who is jealous over the attention that Bess Bart (Mary Kornman, step-daughter of the gang-leader, "Blaze" Bart (George 'Gabby' Hayes), is showing Smokey.
Northwest Mounted Police Corporal Jerry Hale is assigned to take over the district of a fellow-officer, and is puzzled as he had worked this district before and had been mysteriously transferred, disrupting his romance with Helen Brent, the niece of Peter Barkley, the Factor at the trading post. An accountant of the company Berkley works for threatens to expose him when his account is found $10,000 short. Barkley pleads for more time to raise the money. His opportunity arises when he learns that Helen's father and his brother-in-law, Nathan Brent, has struck it rich and is on his way to visit Helen. Barkley instructs his henchmen Carney and Breen to lie in wait and rob Brent of his gold. Brent has a premonition of trouble and buries his gold, making a map of the location. Barkley is disturbed by the arrival of Corporal Hale and goes to warn his men, and finds them already engaged in the attack on Brent. Brent's dog Wolfgang (played by a dog named Rex, or maybe the other way around)...
Learning of Walters' inheritance, Larson kills him and assumes his identity. When Larson's men try to kill Walter's niece Lola, Jack Lane breaks it up. This leads to a showdown with Jack outnumbered by Larson and his gang. Having saved Loma's life earlier, he has Fuzzy ride for him and his men.
Tom Cameron, aka the Lone Rider, and his faithful sidekick, Fuzzy Jones, flee across the Rio Grande to avoid assassination by crooked lawman Deputy Hatfield, only to have the Mexican cops accuse Cameron of being the notorious bandit El Puma. At Hatfield's behest, they are also accused of kidnapping the local mayor's son, and now the pair must prove their innocence and find a way to stop Hatfield's lawless ways.
Gold stages are being held up in the far west at a time when the U.S. government needs bullion, just before the famed "Black Friday" attempt to corner the gold market.
The Colonel sends Fred Dawson and Doc Flanders to investigate a cattleman sheepman war. Posing as a two man medicine show, they quickly become involved. When Fred tries to bring the two sides together, Joe Allison is shot and Fred blamed. With Fred in jail and a lynch mob on the way, Doc tries to break his friend out.
When shifty cattlemen Belknap (Walter Miller) and H.R. Shelby (Gordon Hart) are caught shipping infected animals to Mexico, they frame inspector Gene Autry. Now Autry and his sidekick, Frog Millhouse (Smiley Burnette), must catch the bad guys in the act and set things straight. June Storey co-stars as rancher Martha Wheeler. Autry sings "I'm Gonna Round Up My Blues," "Moonlight on the Ranch House" and "Big Bull Frog."
Young Joe is paralyzed as he is bucked by a wild horse, a strawberry roan. Angered, his father, Walt, tries to shoot the horse but is stopped by his foreman, Gene Autry. The roan escapes and Autry, told to leave the ranch by Walt, finds and trains the horse, now named Champ, in hopes that by returning it to Joe it will provide him with the will to overcome his disability.
Fifteen years after their father was gunned down in cold blood, Cashius and Winston Hurley return to their hometown to avenge his death. Joining forces with their cousin Bugsy, the two gun-slinging brothers hunt down everyone involved in their father's murder. As the bullets fly and the death toll rises, the three young cowboys find themselves fugitives from the law, running for their lives and fighting for their revenge.
Jimmy Dixon, pursued by a band of Mexicans, changes clothes with a tramp, who takes off on his horse. Four miles later, Jimmy walks onto the Double-O Ranch, from which he had been thrown off four years before by his dad, who had blamed Jimmy for something that his twin brother Duke had done. Duke, home from college, took over the ranch when Mr. Dixon became ill, and has run it into the ground. When Duke goes to the bank to repay a debt to Jimmy, he rides onto Phoenix with all of the ranch money.
Tom Keene, formerly George Duryea and latterly Richard Powers, made his final starring appearance in the Monogram western The Painted Trail. Keene is cast as a former federal agent who is drawn out of retirement to stem the activities of smugglers Boss (Leroy Mason) and Driscoll (Walter Long). Disguising himself as an outlaw, our hero gains the confidence of the two desperadoes, only to be found out at the least appropriate time. Rest assured that Keene saves the day and manages to march ingenue Ann (Eleanore Stewart) to the altar.
Cavanaugh and McCauley are after the ranchers land. When the Government announces the land will be put up for auction, the ranchers pool their money only to have it stolen by Cavanaugh's men. They then plan to sell their cattle but Cavanaugh announces a fake gold strike and the cowhands all leave. But Gene's hobo friend the Judge says he will get the cattle to market and he sends out a signal to his hobo friends.
Two women and two kids are stranded in the Old West when bad guys (posing as Indians) try to snag the stagecoach's cargo. Pitted against nature, time, and the pursuing baddies, this unlikely team must trek over the mountains to reach safety.
A young man arrives at the town of Fair Play to see his uncle. What he finds upon arriving is a town hiding a secret from any outsiders. The young man must uncover the truth the townspeople wish to keep hidden in order to save his uncle.
The Trail Blazers are bringing in a prisoner to stand trial for bank robbery, when several attempts are made to kill him; convinced of the man's innocence, they arrange a trap for the real thieves.
Roy is put in charge of a highway construction project. A rancher tries to stop Roy from putting a highway across his land because he fears that the authorities are going to discover the unscrupulous manner in which he got it.