A wagon train of settlers is approaching Prairieville and rancher Allen is out to stop them by having some of his men join the train and poison the horses. When Jack Cameron arrives in Prairieville with replacement horses, he learns his brother who was with the train has been murdered. A piece of his brother's clothing identifies a member of the gang and Jack sets out to find the rest of them and also deliver the horses.
The story revolves around a valuable silver deposit, located between two ranches. Villain Lash Bender cooks up a scheme to gain control of both ranches so that he may have a clear field to the silver lode.
Kirby and Evans are pulling off an irrigation project swindle and newspaper editor Scott realizes it and sends for Lee. Lee agrees with Scott and forms a vigilante group to fight the Sheriff and his deputies brought in by Kirby. But a dying Uncle Dan sets the Sheriff straight and this brings the two sides together for the big shootout.
Donald Barry, not yet Donald "Red" Barry, heads the cast of the Republic western Ghost Valley Raiders. A federal marshal, Barry is assigned to put an end to the activities of a stagecoach-robbery gang. That's why he spends most of the film pretending to be an outlaw himself. Stunt specialist Yakima Canutt plays a secondary villain, and also doubles for Barry in the dicier action scenes.
Union officer Kerry Bradford escapes from a Confederate prison and races to intercept $5 million in gold destined for Confederate coffers. A Confederate sympathizer and a Mexican bandit, each with their own stake in the loot, stand in his way.
Bob Evans' Arabian stallion is stolen and Bob, with his friend Shag Williams starts on the trail that takes them to the horse ranch owned by Kimball and his daughter Ann, where the stallion is running wild. Baker, the ranch's crooked foreman, is utilizing the stallion as a decoy and, with his henchmen, Raymer and Winton, corrals the mares that follow the stallion in a hidden corral, intending to sell them across the state line.
European bad guy Baron Bendor leads some local townsmen in a plot to obtain horses through theft. Hoppy and his sidekicks Lucky and Speedy must find and expose the horse thieves.
Steve Beaumont, an operative for the Cattleman's Protective Association, is assigned the difficult task of breaking up a murderous gang of rustlers led by Ed Brock and Strang. He takes Sheriff Webb, Judge Baxter, and rancher Ann Houston into his confidence, and works his way into the rustler stronghold and confidence by "turning rustler" himself.
Tex and Shorty ride into Cinco Valley, a gold rich area terrorized by marauders ostensibly lead by one Pablo. Tex, however, recognizes Blackie, whose boss is Bannister, an American. Suspecting that Bannister and his henchmen are trying to drive the settlers off their potentially valuable land by posing as Mexican banditos, Tex convinces Pablo to help him set a trap for the marauders.
Unknown to Joan Manning, her trading post partner Weathers is operating a counterfeiting ring. When miner Jim Smithers brings his gold dust in, Weathers pays him off in counterfeit money. Jim's drunken brother, Bill, comes to the post and Weathers hears him say that Jim is leaving the area for good. Weathers sends Hawks to kill Jim and retrieve the bogus money. RCMP Sergeant Renfrew and Constable Kelly find Jim's body, and Renfrew hurries for Jim's cabin to search it. He is attacked by Weathers' men who have found the money. Renfrew is suspicious when Bill Smithers body is found, supposedly a suicide, with a note he had burned the money. This leads the Mounties to suspect counterfeiting. Kelly follows Manti, an Indian who works for Weathers, to the gang's hideout and is captured. But Renfrew is trailing Kelly.
Russell Hayden, taking a break from playing Hopalong Cassidy pictures, stars as Renn Frayne, a college-educated youth heading westward who finds more than he bargained for. Following a terrifying run-in with an outlaw gang, Frayne aligns himself with the heroine Holly Ripple (Jean Parker), whose father's cattle ranch is in danger of falling into the hands of the villains. Victor Jory as Malcolm Lascallie, the wily gambler,
A ranch owner gives the Cheyenne Kid $1000 and sends him off to buy cattle. At the same time he fires a ranch hand and that hand rides ahead and alerts Jeff Baker about the $1000. Bakers' henchman are too late to get the Kid but they kill the rancher paid by the Kid. The Sheriff then arrests the Kid claiming he murdered the rancher to get the money back and that Baker said he then lost it at his gambling table.
Wild Bill Saunders discovers that his uncle Mort has been murdered by an unscrupulous ranch foreman, Matt Brawley. But before he can right Brawley's wrongs, Wild Bill is arrested for a murder he didn't commit. Sidekick Cannonball Sims and disgruntled girl rancher Joan Darcy plot to break Wild Bill out of jail but Brawley is wise to their plan.