Chet Kasedon is after the Indians hidden gold mine but Chief Moya will not reveal it's location. He has also hired mining engineers Gale and Mortimer to locate the mine. When Gale sees Kasedon's cruelty to Moya, he switches sides.
The boys are a dentist and his assistant traveling to the Old West to open a new practice. Once in town, they buy a business--only to wake up the next day and see that the entire population of this bustling town had left for the California gold fields early that morning! Then, they discover an evil plot to sell out these settlers to some hostile Indians, so they spring to the rescue.
In the 1840's Mexico has ceded California to the United States, making life nearly impossible for the Mexican population due to the influx of land and gold-crazy Americans. Farmer Joaquin Murrieta revenges the death of his wife against the four Americans who killed her and is branded an outlaw. The reward for his capture is increased as he subsequently kills the men who brutally murder his brother. Joining with bandit Three Fingered Jack, Murrieta raises an army of disaffected Mexicans and goes on a rampage against the Americans, finally forcing his erstwhile friend, Bill Warren, to lead a posse against him.
A cowboy realizes too late that his girlfriend's father had been cheated out of everything in a crooked card game. He sets out to get revenge on the crooks.
Billy Donovan arrives looking for his sister's killer. When he hires on at the Halloran ranch where the mysterious Phantom has killed all the hands, it's not long before the Phantom shoots him.
Profiteer Alexander Stiles lays claim to a million acres of range in the Pecos River country, but a rancher named Claybor stands in his way as he has already claimed the water-rich location of Sweetwater as his own.
In a town called New Jerusalem, three bandits hold up a bank. After a gun battle with the townspeople, the three robbers retreat into the scorching Arizona desert. There, they happen upon an ill woman stranded with her child. As the mother dies, she begs the men to take care of her infant. The fugitives want to save the baby -- but to do so, they'll have to travel back to New Jerusalem, where they are wanted men. Remade as 3 Godfathers (1949).
Hoppy returns to find Johnny in trouble. Buck Peters has been shot by Porter who made it look like Johnny did it. When Johnny flees he runs into Linda. He takes a liking to her only to learn her father Shanghai is one of Porter's gang. Going after Shanghai, he gets captured by the gang and Porter now plans to kill him. But Hoppy is near by and Johnny will get unexpected help from Shanghai.
Perrin plays a boxer whose manager takes him out to a ranch for training, but Perrin soon discovers the ranch foreman is responsible for a $100,000 jewel heist.
Tex Weaver is working under cover to bring in a gang of bank robbers. When he is killed, Tim Ross, a marksman with Doc Shaw's traveling show, takes over. Posing as a Mexican he lays a trap for the gang.
After having been gone for some time, a cowboy comes home to his ranch to find himself up against a gang involved in smuggling Chinese into the country.
Bolton has organized a feud between the Rork's and the O'Neil's. He has rustled cattle and killed a man putting the blame on Danny O'Neil. Tom Rork has found a bullet with markings on it that he hopes will clear Danny and bring in the real killer.