Orphan Hilda Swanson's prayers are answered when a Swedish-American colonization company agrees to send her to America. Aboard the steamer, she meets Olaf, a young Swede, and Donna, an enemy courier who is posing as a passenger. Learning that the secret service is on her trail, Donna sews secret documents into the hem of Hilda's skirt. She then sends a wire to her comrade Felix Martinez, notifying him to intercept the Swedish girl.
The story takes place in a small struggling mining town located in the foothills of the California mountains at the time of the gold rush. The camp is suffering from a long string of bad luck. With only one woman in their midst, it seems as though the miners have no future. However, the tide turns when a small boy is born. "Thomas Luck" is the first newborn the camp has seen in ages; things are looking up.
John Gregg and his daughter Mary, on their way to Burro Springs, a boom mining town, lose their way and stumble into "Jawbone," a dilapidated town. Here they meet Mike Hernandez, a good-looking bad man. Mary, thinking Mike a gentleman, takes a liking to him. "Cheyenne" Harry, a homely looking good man, comes to Jawbone and Mary believes him to be a weak character. He becomes fascinated with her. Gregg hires Mike Hernandez to guide him to Burro Springs, displaying his small store of gold when paying Hernandez. Later, Gregg and his party become lost in the desert, and run out of water.
Madge Black witnesses her best friend Nan Westland, kissing her husband, successful lawyer Jeffrey Arnold Black, a successful lawyer, and orders Nan from the house. Angered by her refusal to let him explain, Jeffrey leaves his wife and son David, Jeffrey meets Nan on a westbound train. Though he does not love her he offers his protection and the next year they welcome a son, William. Nan pleads with him to divorce Madge and marry her for the sake of their son, but he will refuse. Distraught, she marries Ben Richardson, a client of Jeffrey's client, leaving their son behind. Twenty years pass with David becoming a responsible adult while half-brother William now known as “Rodeo” becomes the leader of a lawless band of robbers. Meanwhile Ben Richardson and Nan have become owners of Chanceland, a gambling-house in Colorado and it is there that things reach a climax between the near identical brothers.
After her mother's death, Mary not only becomes the household slave of her overbearing father, Scottish American Andy MacTavish but also becomes a mother to her little sister Ruth at their home on the Dakota plains.
After being unfaithful to "The Stranger", who committed a murder on her account, Cherry Millard, known as "The Siren", leaves to work in a dance hall in the Western town of Nugget. When Burt Hall arrives in town to deliver a will to the heirs of Bruce McClade, he is captivated by Cherry, who learns of Burt's mission. Discovering that the will dictates that Dr. Langdon, a friend of the family, is to receive $25,000, Cherry decides to impersonate Langdon's daughter Rose and thus gain possession of the money. In the meantime, The Stranger, who has been freed from jail, returns, recognizes Cherry as The Siren and kills her. This frees Burt from her evil spell, and The Stranger, now insane, follows The Siren's spirit into the desert.
A rich Easterner who has always wanted to live in "the Wild West" plans to move to a Western town. Unknown to him, the town's "wild" days are long gone and it is an orderly and civilized place now. The townsmen, not wanting to lose a rich potential resident, contrive to make over the town to suit the young man's fantasy.
Henry Martin receives a letter from Buck Lessen, a convict about to be released from prison, telling him that his time is up and he is going to get him for sending him to prison and marrying his sweetheart, Jane. The Martins and their young daughter move away but Buck learns where they went. Buck is hiding on the porch, planning to ambush Henry when he comes out. Two drunken cowboys ride by firing their pistols. When Henry comes outside he sees Buck's body lying in the grass, shot to death by a stray bullet.
Bored with the ranch, Buck's girl goes off to the city and gets involved (innocently) in a brothel. When Buck brings a herd of cattle to town, a streetwalker lures him to the house just in time for him to save his girl from Martin.
Bob Fulton is the superintendent of a mine in the West. He wins the enmity of dancehall owner Jack King when he saves one of the girls, Rose De Braisy, from his unwanted advances. Fulton also wins Rose's love, which he does not return. The mine's owner sends his troublesome son, Roland Holt, out West to work at the mine. Before Holt leaves the East he secretly marries Beth Hoover. Upon Holt's arrival, Fulton tries to befriend him, but Holt prefers the company of bad-guy King.
William S. Hart was the great solitary Western hero of silent film who rode his horse off to new adventures once his job was done. In WOLF LOWRY, he meets a young settler played by Margery Wilson, herself a director in the early 1920s whose films are all considered lost.
A gambler decides to play one last game before he turns over a new leaf. However, during the game one of the players accuses him of cheating. Suddenly the lights go out, shots are fired and when the lights come back on, one of the players is dead. The gambler is accused of the killing. He didn't do it, but has to find out who did, and why he was framed for it.