The Rancho Grande, a Texas border ranch, cut off from the law by a gang of outlaws led by ranch foreman Bart Lane, who is holding the elderly owner of the ranch, Sarah Burton, a prisoner. Tex Lowery, an undercover Texas Ranger, rescues Martha Williams, a nurse sent for by the ailing Sarah, from a stagecoach holdup by Lane's henchmen. He later convinces Laner that he is a wanted outlaw named Ed Carter, and gains entry to Rancho Grande. But the real Ed Carter shows up.
Lambert has the stagecoach wrecked killing the Commissioner so his phony replacement can alter Coonskin's land survey. When Red Ryder exposes the survey hoax, Lambert has his stooge Sheriff put Red in jail.
Gene Autry and sidekick Frog Millhouse depart Madison Square Garden and NYC heading west for home in their car and a horse trailer carrying Gene's horse, Champion. They discover that Ronnie Willoughby, a young boy just off the boat from school in England, has hitched a ride, thinking that Gene and Frog were sent by his father to meet him. Ronnie thinks his father is a big rancher in the west and doesn't know that his father, Alfred Willoughby, is serving time in San Quentin prison because of a frame-up by the officials of a packing company. To keep the father from testifying against them, the packing company officials, Carter, Jenkins and Martin, have arranged for the boy to be kidnapped. Along the way a runaway bride, Joyce Halloway, and her young sister Patsy join the troupe.
Georgia, 1864. Desperate to escape an arranged marriage to her brutal neighbor, Willa Randall disguises herself as a boy and joins the confederate Cavalry.
Boston pharmacist Tom Craig comes to Sacramento, where he runs afoul of local political boss Britt Dawson, who exacts protection payment from the citizenry. Dawson frames Craig with poisoned medicine, but Craig redeems himself during a Gold Rush epidemic.
A cowboy realizes too late that his girlfriend's father had been cheated out of everything in a crooked card game. He sets out to get revenge on the crooks.
The Shadow and his outlaw gang have control of Durango Valley. Keene Cordner arrives, and with the help of Tanner becomes a second Shadow in his attempt to round up the gang.
Jesse James leaves Missouri for Mississippi, and immediately charms all the women in Mississippi out of their bloomers and garters. His first conquest is the banker's daughter who helps him loot the bank in exchange for a promise of marriage; he wanders over to the saloon and runs the crooked partner of the proprietress out of town, takes all of his-and-her money and leaves her, between kisses, hounding him for her share; the third one, the saloon singer, actually makes a mark out of him as she cons him into a boxing match against a professional fighter and he loses the fight and his money, but he holds the singer and the fighter up as they leave town and gets his money back; and then he romances and swindles Cattle Kate, a replay of what he had done somewhere before to Kate.
Poachers are harassing toll road owner Jen Larrabee. They want her land because it holds valuable minerals. Autry and the Cass County Boys, mistaken for Texas Rangers, help out.
Shortly after Brand kills Gelbert, Tom Rayburn arrives on the scene and is accused of the murder. Escaping, he goes after Doc Mathews, the man that can prove his innocence. Brand is also after Mathews and intends to keep him from testifying. But Mathews is a ventriloquist and this will lead to Brand's downfall.
Jim Bannon is back as enduring cowboy hero Red Ryder in Eagle-Lion's Roll, Thunder, Roll. As ever, Ryder's cohorts are Little Beaver and the Duchess, here played by "Little Brown Jug" and Marin Sais. This time, Ryder tries to prove that a series of cattle raids and ranch fires were not the handiwork of masked Mexican do-gooder El Conejo.