After a stagecoach is robbed and the passengers murdered, a long and tangled series of surprise attacks and murderous double-crosses, leaves the coach's strongbox in the hands of the killer Lasky. It is up to the legendary hero Sartana to track down the missing money and determine just who is ultimately behind the grisly robberies and killings.
After being framed, a cowboy is sent to jail. After his time is served, he leaves with vengeance in his heart. Soon he meets a young Native American woman and together they go to settle their score with a small town and its corrupt leader.
Sartana, bounty hunter and gunfighter, witnesses the robbery of a shipment of gold. He finds his way into town where he meets with a lot of suspicious stares from the locals. He also meets with Samuel Spencer, who seems to own the company in this company town. The gold shipments are being stolen, so Spencer agrees to hire Sartana to protect the next gold shipment. Numerous dull-witted villains make attempts on Sartana's life, but he survives. Eventually, Sartana's nemesis Sabbath (he of the white coat and parasol) rides into town. With a showdown inevitable, Sartana and Sabbath square off to settle the score.
American federal agent Clark Stuart is on assignment in Santa Fe to draw up a trade agreement with the newly installed Mexican governor. Meanwhile, Walter Jamison leads a wagon train from Missouri, hoping to take advantage of the new agreement. Among Jamison's passenger are famed frontiersman Jim Bowie and a very youthful Kit Carson. The destinies of all these personalities intersect when villainous ex-governor DuPrey schemes to undermine the treaty and take over the New Mexico territory for his own vile purposes. Somewhere along the way, Davy Crockett joins the "good guys" in their efforts to thwart the despicable DuPrey.