In old Spanish California, dashing cattleman Juan Obregon returns to the rancho of his friend Gaspar Melo, to find he's fathered a son on Rosa, one of Gaspar's identical twin daughters. Overjoyed, he plans to formalize his "unofficial" marriage. But trouble brews; Melo's land is of unclear title and the new Don Domingo hopes to grab it for his own profit. Violence results. Without even knowing who survived, Juan (accompanied by Rosa's tomboy sister Tonya) rides for revenge, through spectacular pastoral and wilderness scenery.
Sartana, bounty hunter and gunfighter, witnesses the robbery of a shipment of gold. He finds his way into town where he meets with a lot of suspicious stares from the locals. He also meets with Samuel Spencer, who seems to own the company in this company town. The gold shipments are being stolen, so Spencer agrees to hire Sartana to protect the next gold shipment. Numerous dull-witted villains make attempts on Sartana's life, but he survives. Eventually, Sartana's nemesis Sabbath (he of the white coat and parasol) rides into town. With a showdown inevitable, Sartana and Sabbath square off to settle the score.
American federal agent Clark Stuart is on assignment in Santa Fe to draw up a trade agreement with the newly installed Mexican governor. Meanwhile, Walter Jamison leads a wagon train from Missouri, hoping to take advantage of the new agreement. Among Jamison's passenger are famed frontiersman Jim Bowie and a very youthful Kit Carson. The destinies of all these personalities intersect when villainous ex-governor DuPrey schemes to undermine the treaty and take over the New Mexico territory for his own vile purposes. Somewhere along the way, Davy Crockett joins the "good guys" in their efforts to thwart the despicable DuPrey.