Clint Ross's skill at fisticuffs earns him the town marshal's job in Cheyenne. Thanks to the string-pulling of political boss Big Bill Harmon, Ross makes it all the way up to the governor's office. But when Ross figures out that Big Bill is a big crook, it's showdown time.
Three outlaws fleeing a posse through the desert come upon a dying woman and her baby in a wagon. Before she passes away, she makes the men promise to take care of her baby and get it safely through the desert.
Gene Autry heads a cattlemen's association and calls on the inexperienced Jim Agnew to negotiate the sale of five hundred heads of cattle. Jim ends up losing the cattle in a crooked poker game, however, and Gene and his sidekick Frog set out to find the cheating gamblers. It soon becomes clear that the leader of the gamblers is none other than Asa Lock, the dastardly father of Gene's romantic interest Stephanie.
John Vickers has spent eight years hunting for the three men who murdered the woman he loved. He finds one, Woodson, and kills him in a gunfight, but not before learning that the other two men have joined the U.S. Cavalry.
When his life is saved in a shootout by a fellow gunman whose life he in turn had saved, Alex Longmire promises to give up his way of life. Riding into town he finds the only job available is deputy to sheriff Jade Murphy, an honest man caught between small farmers and a local cattle baron. And he has a pretty daughter. So Longmire decides to stay and see if he can use his expertise with firearms for good.
Disturbed by the separation of his friends Mary Smith and Arthur Saxon, who really love each other, William "Red" Saunders resolves to reconcile the couple. Discovering that Belknap, a missionary with political aspirations, exercises a destructive hypnotic influence over Mary, Red schemes to eliminate Belknap.
Capt. Harper's cavalry patrol returns to the fort to find it besieged by Ute Indians. The apparent cause is the recapture of Army traitor Brett Halliday, who deserted to the Utes in a previous war; but Brett has a different story. With capture imminent, the only chance for the surviving men (and one woman) is to boat down a wild, uncharted river, where Harper and Halliday must pull together, like it or not.
Albert Quinn Ingalls wants to be a doctor. But soon he discovers that he is fatally ill. He decides to spend the rest of his life in Walnut Grove. Meanwhile children from school are preparing for their traditional climbing of the mountain.
Tom promises his sweetheart, Vicky, that he will stop drinking. He falls in with boon companions, however, and in a saloon brawl, he accidentally shoots Ned, his pal. The sheriff and Vicky's brother find that Ned was only stunned by the bullet. At a rodeo, Tom meets the sheriff, who arrests Tom for the shooting of Ned.
The Denbow family denies access across their land to homesteaders. To evade a murder charge, Glenn Denbow marries Jane, the only witness who's in love with him. But the woman favors the settlers...
Karukan, a ronin samurai, travels to the old west after his clan fails to stop a beast that has escaped Japan. He hires Langdon, to accompany him to stop the beast from killing.
In the late 1800s, a fanatical religious leader, a renegade Sheriff, and a former prostitute collide in a blood triangle on the rugged plains of the New Mexico Territory.