Will Penny, an aging cowpoke, takes a job on a ranch which requires him to ride the line of the property looking for trespassers or, worse, squatters. He finds that his cabin in the high mountains has been appropriated by a woman whose guide to Oregon has deserted her and her son. Too ashamed to kick mother and child out just as the bitter winter of the mountains sets in, he agrees to share the cabin until the spring thaw. But it isn't just the snow that slowly thaws; the lonely man and woman soon forget their mutual hostility and start developing a deep love for one another.
A white man trades with the Comanche for the release of a female stranger and the pair cross paths with three outlaws who have their eyes on the handsome reward for bringing her home and Comanche on the warpath.
In Apache territory, a supply Army column heads for the next fort, an ex-scout searches for the killer of his Native wife, and a housewife abandons her husband to rejoin her Apache lover's tribe.
At the beginning of the 1913 Mexican Revolution, greedy bandit Juan Miranda and idealist John H. Mallory, an Irish Republican Army explosives expert on the lam from the British, fall in with a band of revolutionaries plotting to strike a national bank. When it turns out that the government has been using the bank as a hiding place for illegally detained political prisoners -- who are freed by the blast -- Miranda becomes a revolutionary hero against his will.
A small-town sheriff in the American West enlists the help of a disabled man, a drunk, and a young gunfighter in his efforts to hold in jail the brother of the local bad guy.
Will Kane, the sheriff of a small town in New Mexico, learns a notorious outlaw he put in jail has been freed, and will be arriving on the noon train. Knowing the outlaw and his gang are coming to kill him, Kane is determined to stand his ground, so he attempts to gather a posse from among the local townspeople.
Master gunslinger Sabata arrives in Hobsonville, a town completely owned by McIntock, a robber baron who is taxing the inhabitants for the cost of future improvements to the town. Or that's what McIntock says he'll do with the money...
Arms dealer Yolaf Peterson aims to make a sale to guerilla Mongo, but the money is locked in a bank safe, the combination known only to Professor Xantos, a prisoner of the Americans. Yolaf agrees to free Xantos, accompanied by reluctant guerilla Basco, but a former business partner of Yolaf's- John 'The Wooden Hand', has other ideas.
When the members of a caravan of pioneers find a daisy growing in the middle of the desert they decide to stop there and to build their town on this very spot. Houses soon spring up like mushrooms, immediately followed by a bank, a saloon, a prison, etc. Daisy Town is born. Unfortunately a city does not go without its bad boys and the peaceful place is soon turned into a lawless place. To restore law and order, a lawman is needed. Lucky Luke, the cowboy who shoots faster than his shadow, will be this man: all the villains had better watch out!
The story opens in a Western saloon, where a young musician with a banjo begins to tell a tale of Lucky Luke and his sworn enemies the Dalton brothers: Joe, William, Jack and Averell. Luke has, once again, as he has done many times before, thrown the four outlaws into jail. The prison is also the abode of a guard dog named Rin Tin Can (Rantanplan in the original French language version).
In this strange western version of Moby Dick, Wild Bill Hickok hunts a white buffalo he has seen in a dream. Hickok moves through a variety of uniquely authentic western locations - dim, filthy, makeshift taverns; freezing, slaughterhouse-like frontier towns and beautifully desolate high country - before improbably teaming up with a young Crazy Horse to pursue the creature.
While passing through the town of Bannock, a bunch of drunken cattlemen go overboard with their celebrating and accidentally kill an old man with a stray shot. They return home to Sabbath unaware of his death. Bannock lawman Jered Maddox later arrives there to arrest everyone involved on a charge of murder. Sabbath is run by land baron Vince Bronson, a benevolent despot, who, upon hearing of the death, offers restitution for the incident.
The Apache Indians have reluctantly agreed to settle on a US Government approved reservation. Not all the Apaches are able to adapt to the life of corn farmers. One in particular, Geronimo, is restless. Pushed over the edge by broken promises and necessary actions by the government, Geronimo and thirty or so other warriors form an attack team which humiliates the government by evading capture, while reclaiming what is rightfully theirs.
Henry Moon is captured for a capital offense by a posse when his horse quits while trying to escape to Mexico. He finds that there is a post-Civil War law in the small town that any single or widowed woman can save him from the gallows by marrying him.