Los Reyes County, Arizona. Leland, a retired lawman, works with Wallace, the new sheriff who replaces him, when a vicious hit man, sent by a Mexican drug cartel, threatens their border small town.
Afflicted with a terminal illness John Bernard Books, the last of the legendary gunfighters, quietly returns to Carson City for medical attention from his old friend Dr. Hostetler. Aware that his days are numbered, the troubled man seeks solace and peace in a boarding house run by a widow and her son. However, it is not Books' fate to die in peace, as he becomes embroiled in one last valiant battle.
Three of the original five "young guns" — Billy the Kid, Jose Chavez y Chavez, and Doc Scurlock — return in Young Guns, Part 2, which is the story of Billy the Kid and his race to safety in Old Mexico while being trailed by a group of government agents led by Pat Garrett.
John Henry returns to his hometown in hopes of repairing his relationship with his estranged father, but a local gang is terrorizing the town. John Henry is the only one who can stop them, however he has abandoned both his gun and reputation as a fearless quick-draw killer.
In this radically reimagined American Western set towards the end of the Civil War, Southerner Augusta encounters two renegade, drunken soldiers who are on a mission of pillage and violence. After escaping an attempted assault, Augusta races back to the isolated farmhouse that she shares with her sister Louise and their female slave Mad. When the pair of soldiers track Augusta down intent on exacting revenge, the trio of women are forced to take up arms to fend off their assailants, finding ways to resourcefully defend their home––and themselves––as the escalating attacks become more unpredictable and relentless.
When three women living on the edge of the American frontier are driven mad by harsh pioneer life, the task of saving them falls to the pious, independent-minded Mary Bee Cuddy. Transporting the women by covered wagon to Iowa, she soon realizes just how daunting the journey will be, and employs a low-life drifter, George Briggs, to join her. The unlikely pair and the three women head east, where a waiting minister and his wife have offered to take the women in. But the group first must traverse the harsh Nebraska Territories marked by stark beauty, psychological peril and constant threat.
In a future where water is scarce, a farmer defends his land and hopes to rejuvenate his parched soil. However, his daughter's boyfriend schemes to steal the land for himself.
After her outlaw husband returns home shot with eight bullets and barely alive, Jane reluctantly reaches out to an ex-lover who she hasn't seen in over ten years to help her defend her farm when the time comes that her husband's gang eventually tracks him down to finish the job.
In the late 1800s, a fanatical religious leader, a renegade Sheriff, and a former prostitute collide in a blood triangle on the rugged plains of the New Mexico Territory.
An outlaw named Guerrero Hernandez is shot in the back and killed whilst attempting to free his half-brother from a small-town prison. Making a deal with the devil, Hernandez returns from the dead to take his revenge.
In Bolivia, Butch Cassidy (now calling himself James Blackthorn) pines for one last sight of home, an adventure that aligns him with a young robber and makes the duo a target for gangs and lawmen alike.
When a nun broke her covenant with God to save the life of her unborn son, Aman, he was cursed for life. As an adult, Aman has killed those who have crossed him. But his curse brings his victims back to life and they pursue him for revenge, so Aman enlists a young gunman to fight by his side against his undead victims.
Gunslinger Jonah Hex is appointed by President Ulysses Grant to track down terrorist Quentin Turnbull, a former Confederate officer determined on unleashing hell on earth. Jonah not only secures freedom by accepting this task, he also gets revenge on the man who slayed his wife and child.