When his well-meaning sidekick (Smiley Burnette) buys a cow farm instead of a cattle ranch, singing cowpoke Gene Autry prepares to embrace the dairy business. But with a corrupt association bent on driving up milk prices, it's up to newly elected Sheriff Gene to clean up the mess. Country music icon Patsy Montana sings "I Want to Be a Cowboy's Sweetheart," while radio crooners the Texas Rangers perform alongside Autry.
An elderly man leaves Wyoming to visit his daughter in a small Massachusetts town because, even though she didn't say so, he believes she needs his help. When he gets there he discovers that his daughter, a lawyer, is under great stress because of her biggest client, an old geezer who is the wealthiest and most powerful man in town. The girl's father decides to make the old man "disappear" by performing a rain dance he learned from an Indian chief back in Wyoming--and lo and behold it starts to rain and the old man does indeed disappear. The local sheriff, however, suspects foul play and arrests the girl's father.
When a farmer's wife is brutally murdered by the ruthless bandit Bobby Durango and his gang of killers, Billy Rogers goes back to his old gun and starts to hunt them one by one.
Gene takes care of three tough kids sent west from Chicago after their father died and left them a cattle ranch. They help him catch a bunch of rustlers.
When attacked by two dogs, Joe Gilmore leaves them on the desert to die. Later one of the dogs saves John Blake from drowning. Men arrive claiming the dog is killing their chickens. They want to kill the dog but John convinces them the dog's fate should be determined by a trial.
Gene Autry hunts bank robbers Al Bartlett and Trot Lucas with his old friend Mike. Bartlett, to throw off his pursuers, kills Trot and his own brother. When Kitty Bartlett comes to town claiming to be the slain Bartlett's widow, Gene has to save her from the irate townspeople who are not aware that her name isn't Bartlett but she really is the daughter of a law officer slain by Al Bartlett. Ben Luder, a local hood, tricks Bartlett back into town by saying he has to fixed to have Doc Larry Taylor do plastic surgery on him. En route they meet Doc and his assistant Helen Ellis and Ben's ruse is exposed. Bartlett kills Ben and forces Doc to drive him to the railroad. Gene, in a fight atop a runaway train, captures Bartlett.
President Lincoln personally sends Bill Gibson west to see if he can stop the holdups of the needed shipments of gold. There he meets his boyhood friend Foster. When all others refuse to take out the next gold shipment due to the killings, Bill volunteers. Jeannie, afraid for his safety, tells Foster of Bill's secret route not knowing Foster is the leader of the outlaw gang.
Native son returns from school in Spain to California in 1855 and finds corrupt politicians stealing land from old California families. He becomes a sort of Robin Hood in order to fight them.
Gene Autry becomes the new Sheriff after bank robbers kill the former sheriff. When Judge Beaumont is murdered, evidence points to the judge's wild son. Believing the young man, Gene tries to help.
Hanley shoots a man and then frames Bill Roberts. Being the Judge he then holds court planning to hang Bill but Bill's friends effect his escape. Andy tries to lead Hanley astray by misleading him as to Bill's location. But Bill changes plans and Hanley catches up with him and this leads to the showdown.
A ranch owner fires his ranch hands and brings in women to replace them. The owner's daughter wants the male hands back and comes up with a plan to do it.
Lawyer Creech is after the ranch of the dying Cartwright. First he brings in Cahill to pose as the only living relative. Then when the Tonto Kid finds platinum on the ranch, Creech frames him for murder.