Rodeo champ Gene Autry inherits half interest in both a ranch and a mine that provides steady employment for the surrounding rancheros. Unfortunately, the other half goes to Easterner Barbara Erwin (Carol Hughes), who is only interested in monetary remuneration. To convince Gene to buy her share, Barbara enters into an unholy alliance with unscrupulous attorneys Arnold (Ivan Miller) and Fry (Sam Flint), who, without their client's consent, hire a gang of thugs headed by Tommick (John Merton). When a ranchero (Elias Gamboa) is mortally wounded in the ensuing gun battle, Barbara sees the error of her way and switches sides.
Belle Langtry runs a town being taken over by cattle rustlers. She is also a front for the outlaws, who are led by Steve Fraser. Hoppy gets elected sheriff and cleans up the town with help from the Bar 20 boys.
The Rough Riders are called in to help save Master's stage line. Taggart has his gang robbing the stages and shooting the drivers. When Buck drives the next stage, Taggart's men rob it and then make it look like Roberts is part of the gang. Written by Maurice Van Auken
The conflict between a railroader and a stage line owner is being aggravated by bad guys who are sabotaging both sides. Roy and Gabby mediate the conflict and expose the bad guys.
The notorious outlaw Black Bart has reappeared and the Range Busters are sent to investigate. When they find that Black Bart is now a respectable citizen and that someone is impersonating him, they set a trap for the robber.
Hoppy, Lucky and California search for a mine owned by Trudy Pendleton after it was taken from her by thw swindling gambler Ace Gibson. They find the mine and Hoppy fights Gibson over it.
The mayor has sent for a gunslinger who, though appearing to clean up the town, is really to be the mayor's means of taking the town over. When Roy and Gabby arrive in Tombstone, Roy is mistaken for the gunslinger. Just as Roy is ready to expose the mayor, the real gunslinger shows up.
Roy is a newspaper reporter. He goes to Cheyenne to cover the activities of supposed bad guy Arapahoe Brown. Roy, of course, discovers who the real bad guy is.
Gene returns from the East with new ranch owner Tom Bennett to find everyone's cattle dying. Blaine has reopened the copper mine and the waste is poisoning the water supply. While Gene is away Tom confronts the miners and a man is killed in the ensuing gunfight. Now Gene not only has the dying cattle problem but his ranch owner is in jail.
Joe Weller has instigated a conflict over water rights between two ranchers. The idea is to have the ranchers do each other in then move in and take over. Hoppy and the good guys won't let this happen.
The fifth film in the 24-film Range Busters series finds "Crash", "Dusty" and Alibi, on their way to Gopher City to become the town's peace officers. In the saloon, young Jimmy Rowell is losing money in a crooked poker game to saloon owner Bob Harmon. Harmon and his henchman Bart Gill are in reality wanted-outlaw brothers Jim and Ike Breedon seeking revenge against Jimmy and his school-teaching sister Sally as their father, a circuit judge in Nebraska, had sentenced their brother Bud to be hanged. Harmon involves Jimmy, because of his gambling debts, in a robbery of a rancher known to keep large amounts of money at his ranch. The Range Busters break up the robbery, Bart is killed, as is Rancher Fleming, and Jimmy is wounded but escapes. Harmon, setting a trap for Crash, tricks Sally and Jimmy to his hideout, and Crash follows them.
When the showboat hits town, two men use the parade as a distraction to rob the bank. Their accomplice is Pop, the clown from the showboat. He leaves the money on the boat and tells his daughter Patsy to bring it to him at a later stop on the river. Gene's investigation of a bank robbery takes him to the showboat where he becomes a performer. Gene and Frog try to find the money while helping Patsy and her father.
Stephen Westcott and Ed Martin scheme to put Jane Travers' wagon line out of business. They want to use it take over all the wagon- train traffic going west. Hoppy, California and Lucky must make sure that doesn't happen.
As a penalty for fighting fellow classmates days before graduating from West Point, J.E.B. Stuart, George Armstrong Custer and four friends are assigned to the 2nd Cavalry, stationed at Fort Leavenworth. While there they aid in the capture and execution of the abolitionist, John Brown following the Battle of Harper's Ferry.
Wanted by the law in New York, Dr. Steve Kells heads west and arrives in an area controlled by an outlaw gang known as the Border Legion. When the gang's boss is wounded, they kidnap Kells and force him to remove the bullet. Not allowed to leave and being a wanted man, he joins the gang. Now wanted as a gang member also, he nevertheless plans a raid that will lead the entire gang into a trap.