Ann Fenwick is a witness to a bank robbery in the U.S. and the bandits, led by Trigger and Leon capture her and when she disappears, a warrant is issued for her arrest as a material witness. The bank robbers flee across the border into Canada where they steal a trailer in which they lock Ann and the loot. The hitch breaks and the trailer plunges into a lake. Sergeant Renfrew and Constable Kelly, of the Canadian Mounties, rescue Ann and she tells them she is a hitch-hiking tourist and gives a false name. Renfrew sends Kelly for aid, Ann escapes and Kelly returns with the news that she is wanted. The leader of the gang, Cardigan, sends the gang back for Ann and the loot, which Ann has hidden in a trappers cabin, just before Trigger recaptures her. Renfrew goes to her rescue, but is also captured. But reliable Constable Kelly is somewhere in the woods.
Cowhand Ken Clark is stranded in Chicago, and temporarily takes a job as a sharp-shooter entertainer in a night club, with the intention of getting enough money together to get back to his beloved Arizona. Frank Gordon, while drunk, is about to be rolled by the club bouncer, but Ken interferes and earns Clark's gratitude. Gordon gets a telegram from Kay Burke, the daughter of his partner in Arizona, notifying him that her father, Jim Burke, has been killed by rustlers.The ranch has a U.S. Army contract to furnish horses, but she sees little hope of being able to make good because the stock is being rustled, and she asks Gordon for his help.
Buck Colins heads a group of local ranchers who are trying to prevent the railroad from completing its line through their property. Till now they have been able to charge tolls on herds passing through. Hoppy goes undercover to expose them.
Before he was killed, Martin hid a half million dollars worth of bonds on his ranch. Brainard, who killed him, Inspector Carson posing as Sam Brown, and Martin's niece Margaret all want the ranch, and it's being sold at auction.
When his ranch falls on hard times, Cowboy Roy Roger has trouble making his mortgage payment and he takes his song and dance to Wall Street to try to raise cash fast.
When his well-meaning sidekick (Smiley Burnette) buys a cow farm instead of a cattle ranch, singing cowpoke Gene Autry prepares to embrace the dairy business. But with a corrupt association bent on driving up milk prices, it's up to newly elected Sheriff Gene to clean up the mess. Country music icon Patsy Montana sings "I Want to Be a Cowboy's Sweetheart," while radio crooners the Texas Rangers perform alongside Autry.
Hoppy goes to town to help Marshal Windy with some rustlers and winds up helping the widow Joyce when confidence men try to take her herd. King's Men songs include: "Hi Thar Stranger" and "Lazy Rolls the Rio Grande."
Tex arrives on the Parker ranch on Christman eve and is given the job of being Santa Claus. Also dressed as Santa Claus, Blackie robs Parker and kills a man. When Tex is arrested for the murder, he escapes and joins up with outlaw Becker and his gang. He finds Blackie's Santa Claus suit but is soon made a prisoner.
Cavanaugh and McCauley are after the ranchers land. When the Government announces the land will be put up for auction, the ranchers pool their money only to have it stolen by Cavanaugh's men. They then plan to sell their cattle but Cavanaugh announces a fake gold strike and the cowhands all leave. But Gene's hobo friend the Judge says he will get the cattle to market and he sends out a signal to his hobo friends.
Two young brothers are separated when their wagon train is attacked and their parents killed. One brother Cherokee is raised by Indians and the other, the Kansas Kid, by the outlaw gang leader Buff. Twenty years later they unknowingly meet again when the Kid goes after wagons being guided by Cherokee.
In the midst of the Civil War, Lassiter has a plan to get control of California. Working out of St. Joseph, he plans to send forged messages to the troops on the west coast via Pony Express. First he attempts to bribe Pony Express ride Roy Rogers. When Roy refuses he turns to the outlaw Johnson and his gang and this leads to trouble.
Roy and Gabby return to Gabby's Texas ranch, after fighting with the Confederate military during the American Civil War, to find that a blustery Union Colonel whom they have previously hassled is now their district commander. Unbeknownst to the Colonel, however, is that the soldiers he believes have been sent to assist him are actually Union Army rejects who have come to loot the civilian populace under the guise of reinstituting normalcy to the former Confederate district.
Roy Rogers is a cowboy who joins the Border Patrol, only to have his buddy Tommy get killed at a local saloon. Determined to get revenge at any cost, Roy and Rusty cross the border in search of Arizona Jack, the man responsible for Tommy's death.
A group of people traveling on a stagecoach find their journey complicated by the threat of Geronimo, and learn something about each other in the process.
When shifty cattlemen Belknap (Walter Miller) and H.R. Shelby (Gordon Hart) are caught shipping infected animals to Mexico, they frame inspector Gene Autry. Now Autry and his sidekick, Frog Millhouse (Smiley Burnette), must catch the bad guys in the act and set things straight. June Storey co-stars as rancher Martha Wheeler. Autry sings "I'm Gonna Round Up My Blues," "Moonlight on the Ranch House" and "Big Bull Frog."