The Government sends Dean, Baxter, and Gordon to investigate a series of train holdups. Travis is behind the robberies and they are soon on his trail. When things get hot, Travis has a plan of double-crossing his own men that will enable him to keep not only his gold but also the money it is insured for.
The arrival of the telegraph put Pony Express riders like John Blair and his pal Smoky out of work. A race will decide whether they or stageline owner Drake get the government mail contract.
The story is set in the British province of New York during the French and Indian War, and concerns—in part—a Huron massacre (with passive French acquiescence) of between 500 to 1,500 Anglo-American troops, who had honorably surrendered at Fort William Henry, plus some women and servants; the kidnapping of two sisters, daughters of the British commander; and their rescue by the last Mohicans.
Doran and the Sheriff have a scheme to bring in an outlaw gang. Doran is sent to prison so he and the gang leader Mitchell can break out. This gets him into the gang but he is in trouble when it's revealed he is working with the Sheriff.
Chet Kasedon is after the Indians hidden gold mine but Chief Moya will not reveal it's location. He has also hired mining engineers Gale and Mortimer to locate the mine. When Gale sees Kasedon's cruelty to Moya, he switches sides.
An old miner is ambushed by outlaws trying to steal the $10,000 he is carrying to start up a new mine. A passing cowboy comes to the miner's aid, but winds up getting blamed for the attack.
Although Larry "Buster" Crabbe earns top billing, the hero of Drift Fence is former Western star Tom Keene as Jim Travis, who, at a rodeo, meets city dweller Jim Traft, who has come west to erect a fence that will prevent Clay Jackson from continuing his cattle rustling business. A tough Western type, Travis suggests that he impersonate Traft and the building of the fence soon begins. But Travis is opposed by Slinger Dunn and his family, whose small ranch will suffer from the division of the land. A romance between Travis and Slinger's sister, Paula, paves the way for a meeting of the minds, however, and Slinger switches sides completely upon learning that Travis is a Texas Ranger in disguise.
A miner who was swindled out of his mine by a banker turns to robbing stagecoaches. Several years after he is tracked down and killed, his son comes to town to tangle with the banker.
Jack is looking for the man that was responsible for the death of his sister after he hired her as a school teacher. When he runs into school teacher Ann who was just hired by Corey, he soon realizes Corey is the man he is after. Lacking proof, he works on Corey's nerves hoping to get a confession from him.
Kirk Baxter has been sent to investigate murder and robbery involving gold shipments. Identifying a gang member by his bullets, he uses that man's horse to locate and join the gang. He learns the gang is tipped off to the shipments by a mine employee using carrier pigeons. But the next message reveals his true identity and he is made a prisoner.
Rigging a horse race, Don Carlos wins a lot of money. When he loses his winnings at the gambling table, he shoots the dealer with Horton's gun. Horton is arrested but cannot prove his innocence.